可扩展的、无金属且无添加剂的卤代芳烃和季铵盐的光致硼化反应
Scalable, Metal- and Additive-Free, Photoinduced Borylation of Haloarenes and Quaternary Arylammonium Salts.
作者信息
Mfuh Adelphe M, Doyle John D, Chhetri Bhuwan, Arman Hadi D, Larionov Oleg V
机构信息
Department of Chemistry, The University of Texas at San Antonio , San Antonio, Texas 78249, United States.
出版信息
J Am Chem Soc. 2016 Mar 9;138(9):2985-8. doi: 10.1021/jacs.6b01376. Epub 2016 Mar 1.
Abstract
We report herein a simple, metal- and additive-free, photoinduced borylation of haloarenes, including electron-rich fluoroarenes, as well as arylammonium salts directly to boronic acids. This borylation method has a broad scope and functional group tolerance. We show that it can be further extended to boronic esters and carried out on gram scale as well as under flow conditions.
摘要
我们在此报告一种简单的、无金属和添加剂的、光诱导的卤代芳烃（包括富电子氟代芳烃）以及芳基铵盐直接硼化生成硼酸的方法。这种硼化方法具有广泛的适用范围和官能团耐受性。我们表明它可以进一步扩展到硼酸酯，并且可以在克级规模以及流动条件下进行。
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