Lontie M
J Pharm Belg. 1989 Jul-Aug;44(4):292-301.
The new quinolones are reviewed. These drugs are fluorinated derivatives of nalidixic acid, like ciprofloxacin, norfloxacin, ofloxacin, pefloxacin, and others. The following aspects are discussed: microbiology, modes of action and of resistance, the pharmacologic properties, the adverse reactions, the interactions with other drugs, and the principal clinical applications.
对新型喹诺酮类药物进行了综述。这些药物是萘啶酸的氟化衍生物,如环丙沙星、诺氟沙星、氧氟沙星、培氟沙星等。讨论了以下几个方面:微生物学、作用方式与耐药性、药理特性、不良反应、与其他药物的相互作用以及主要临床应用。