Gao Zhimei, Zeng Yongming, Sun Jingkun, Yang Jingjie, Zhou Yang, Zhou Mi, Song Tingni
The First Affiliated Hospital of Chongqing Medical University, China.
The First Affiliated Hospital of Chongqing Medical University, China
Interv Neuroradiol. 2016 Jun;22(3):287-92. doi: 10.1177/1591019916631980. Epub 2016 Feb 24.
The objective of this article is to explore the feasibility of low injection rate and low contrast agent dose in three-dimensional rotational digital subtraction angiography (3D DSA) of the intracranial aneurysm.
Fifty-one patients with suspected intracranial aneurysms were included. The catheter tip was kept within the internal carotid artery at the epistropheus level. Patients were divided into three groups randomly according to injection rate: group A (1.5 ml/s, n = 18), group B (2.0 ml/s, n = 18), and group C (3.0 ml/s, n = 15). The noise, signal-to-noise ratio (SNR), and carrier-to-noise ratio (CNR) of C2, C6, M1, and A1 segments were calculated. The continuous subtraction images and reconstructed images were evaluated by two technicians.
No significant differences were found in noise between groups A and B, and groups A and C. Significant differences were found in the SNR and CNR of M1 and A1 segments between groups A and B, and groups B and C, but for C2 and C6 segments, they were not significant. Significant differences were found in the SNR and CNR of all segments between groups A and C. Significant differences were found in the contrast agent dose between all three groups. No significant differences were found in scores evaluated by two physicians between the three groups.
The personalized injection protocol of low injection rate and low contrast agent dose in 3D DSA of the intracranial aneurysm is feasible. The application of this protocol can reduce the dose of iodine and obtain satisfactory images.
本文旨在探讨低注射速率和低造影剂剂量在颅内动脉瘤三维旋转数字减影血管造影（3D DSA）中的可行性。
纳入51例疑似颅内动脉瘤患者。将导管尖端置于寰椎水平的颈内动脉内。根据注射速率将患者随机分为三组：A组（1.5 ml/s，n = 18）、B组（2.0 ml/s，n = 18）和C组（3.0 ml/s，n = 15）。计算C2、C6、M1和A1节段的噪声、信噪比（SNR）和载噪比（CNR）。由两名技术人员对连续减影图像和重建图像进行评估。
A组与B组、A组与C组之间噪声无显著差异。A组与B组、B组与C组之间M1和A1节段的SNR和CNR存在显著差异，但C2和C6节段差异不显著。A组与C组之间所有节段的SNR和CNR均存在显著差异。三组之间造影剂剂量存在显著差异。三位医生评估的分数在三组之间无显著差异。
颅内动脉瘤3D DSA中低注射速率和低造影剂剂量的个性化注射方案是可行的。该方案的应用可减少碘剂量并获得满意的图像。
