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恩诺沙星:一种新型抗菌剂。

Enrofloxacin: a new antimicrobial agent.

作者信息

Schroder J

机构信息

Bayer (SA) Animal Health Division, Isando, Republic of South Africa.

出版信息

J S Afr Vet Assoc. 1989 Jun;60(2):122-4.

PMID:2691696
Abstract

A review is given of available literature on a new antimicrobial agent, enrofloxacin. The chemical is a quinolone carboxylic acid derivative, and has a broad spectrum of activity against Gram-positive and Gram-negative bacteria as well as against Mycoplasma spp. in various animals. Several formulations and routes of administration have been tested, and equally good absorption and efficacy have been demonstrated after oral and parenteral administration. In South Africa, a 10% solution for use in the drinking water of poultry, has been registered, while different formulations for other species are still under development.

摘要

对一种新型抗菌剂恩诺沙星的现有文献进行了综述。该化学物质是喹诺酮羧酸衍生物,对各种动物的革兰氏阳性菌和革兰氏阴性菌以及支原体具有广泛的活性。已经测试了几种制剂和给药途径,口服和肠胃外给药后均显示出同样良好的吸收和疗效。在南非,一种用于家禽饮用水的10%溶液已获注册,而针对其他物种的不同制剂仍在研发中。

相似文献

1
Enrofloxacin: a new antimicrobial agent.恩诺沙星:一种新型抗菌剂。
J S Afr Vet Assoc. 1989 Jun;60(2):122-4.
2
Pharmacokinetic and residue studies of quinolone compounds and olaquindox in poultry.喹诺酮类化合物和喹乙醇在家禽体内的药代动力学及残留研究。
Ann Rech Vet. 1990;21 Suppl 1:137S-144S.
3
[In vitro evaluation of lomefloxacin].[洛美沙星的体外评价]
Arzneimittelforschung. 1989 Aug;39(8):832-5.
4
The fluoroquinolone antimicrobials: structure, antimicrobial activity, pharmacokinetics, clinical use in domestic animals and toxicity.氟喹诺酮类抗菌药:结构、抗菌活性、药代动力学、在家畜中的临床应用及毒性
Cornell Vet. 1990 Apr;80(2):173-86.
5
Pharmacokinetic study of danofloxacin in cattle and swine.达氟沙星在牛和猪体内的药代动力学研究。
Am J Vet Res. 1992 Jun;53(6):1022-6.
6
Veterinary use of new quinolones in Japan.日本新型喹诺酮类药物的兽用情况
Drugs. 1995;49 Suppl 2:152-8. doi: 10.2165/00003495-199500492-00025.
7
Serum concentrations and pharmacokinetics of enrofloxacin after intravenous and intragastric administration to mares.恩诺沙星静脉注射和灌胃给药后母马的血清浓度及药代动力学
Can J Vet Res. 2000 Jul;64(3):171-7.
8
Enrofloxacin in salmonids.恩诺沙星在鲑科鱼类中的应用。
Vet Hum Toxicol. 1991;33 Suppl 1:46-8.
9
Plasma concentrations of enrofloxacin in African grey parrots treated with medicated water.用加药饮水治疗的非洲灰鹦鹉中恩诺沙星的血浆浓度。
Avian Dis. 1990 Oct-Dec;34(4):1017-22.
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Pharmacokinetics, stability, and retrospective analysis of use of an oral gel formulation of the bovine injectable enrofloxacin in horses.牛用注射用恩诺沙星口服凝胶制剂在马体内的药代动力学、稳定性及使用情况回顾性分析
Vet Ther. 2004 Summer;5(2):155-67.

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Effects of antibiotics (enrofloxacin) on microbial community of water and sediment in an aquatic ecological model.抗生素(恩诺沙星)对水生生态模型中水体和沉积物微生物群落的影响。
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Genomic Insights Into the Pathogenicity of a Novel Biofilm-Forming sp. Bacteria () Identified in Reptiles.对在爬行动物中鉴定出的一种新型生物膜形成细菌()致病性的基因组洞察。
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恩诺沙星单剂量口服给药后,亚洲家壁虎体内恩诺沙星及其代谢产物环丙沙星的药代动力学特征。
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Effect of Antibiotic Class on Stroke Outcome.抗生素类别对中风预后的影响。
Stroke. 2015 Aug;46(8):2287-92. doi: 10.1161/STROKEAHA.115.008663. Epub 2015 Jul 2.
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Preparation and evaluation of enrofloxacin microspheres and tissue distribution in rats.恩诺沙星微球的制备、评价及其在大鼠体内的组织分布
J Vet Sci. 2015;16(2):157-64. doi: 10.4142/jvs.2015.16.2.157. Epub 2015 Jan 30.
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Comparative activity of pradofloxacin, enrofloxacin, and azithromycin against Bartonella henselae isolates collected from cats and a human.比较普多氟沙星、恩诺沙星和阿奇霉素对从猫和人类分离的巴尔通体亨氏亚种的活性。
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Successful treatment of bacterial infection hinders development of acquired immunity.细菌感染的成功治疗会阻碍获得性免疫的发展。
J Immunol. 2009 Jul 15;183(2):1263-70. doi: 10.4049/jimmunol.0900772. Epub 2009 Jun 19.
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Retinal safety of a new fluoroquinolone, pradofloxacin, in cats: assessment with electroretinography.新型氟喹诺酮类药物普拉德氟沙星对猫视网膜的安全性:视网膜电图评估
Doc Ophthalmol. 2008 May;116(3):177-91. doi: 10.1007/s10633-007-9081-x. Epub 2007 Oct 2.
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Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intramuscular administration of enrofloxacin in goats.恩诺沙星在山羊体内肌肉注射后恩诺沙星及其代谢产物环丙沙星的药代动力学
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Use of antimicrobial drugs in veterinary practice.抗菌药物在兽医实践中的应用。
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