Sezai Y
Kyobu Geka. 1989 Jul;42(8 Suppl):670-6.
In an attempt to save patients with severe cardiac pump failure to which no emergency methods of treatment show effect even with various medications or machinery assisted circulation, the ventricular assisted device (VAD) has come more and more in need today as it provides patients with a temporary cardiac function and serves as a life-prolongation means, eventually aiming at patients' return to normal daily life. In Japan, basic researches for development of VAD have been proceeding since 1960. We have been pursuing researches in the related scientific field since 1980 with the theme of clinical application of VAD and have completed the total system of VAD in August, 1982. In October 1982, we succeeded for the first time in Japan in weaning a patient from the VAD. Until April, 1988 we had managed clinical applications of VAD in 121 cases. Based on this experience, I have presented here a result of our clinical analysis of these cases and have come up with the problems surrounding the clinical application of VAD.
为挽救患有严重心脏泵衰竭的患者，即使使用各种药物或机械辅助循环，紧急治疗方法也无效，心室辅助装置（VAD）如今变得越来越必要，因为它为患者提供临时心脏功能，并作为延长生命的手段，最终目标是让患者恢复正常日常生活。在日本，自1960年以来一直在进行VAD开发的基础研究。自1980年以来，我们一直以VAD的临床应用为主题在相关科学领域进行研究，并于1982年8月完成了VAD的整个系统。1982年10月，我们在日本首次成功使一名患者脱离VAD。截至1988年4月，我们已对121例患者进行了VAD的临床应用管理。基于这一经验，我在此展示了我们对这些病例的临床分析结果，并提出了VAD临床应用中存在的问题。
