Rezende M, Ferri L, Kossatz S, Loguercio A D, Reis A
Oper Dent. 2016 Jul-Aug;41(4):388-96. doi: 10.2341/15-266-C. Epub 2016 Feb 26.
The aim of this study was to evaluate the efficacy, color stability, risk, and intensity of tooth sensitivity (TS) of combined bleaching techniques performed with 20% or 35% hydrogen peroxide for an in-office protocol.
Thirty patients were randomly divided into two groups and submitted to a single 45-minute in-office bleaching session with 35% hydrogen peroxide or 20% hydrogen peroxide. At-home bleaching was performed with 10% carbamide peroxide for two hours daily over the course of two weeks. The color was evaluated with the value-oriented shade guide Vita Classical at different periods up to 12 months after bleaching. Patients recorded the intensity of TS using a five-point verbal scale. Color change data were submitted to a two-way repeated-measures analysis of variance and Tukey test (α=0.05). The absolute risk and intensity of TS were compared with the Fisher exact test and Mann-Whitney test, respectively (α=0.05).
On average, an effective and similar whitening of three units in shade guide was observed for both groups, which remained stable for 12 months. When both protocols were compared, the one with hydrogen peroxide 35% showed a higher risk (p=0.02) and intensity of TS (p=0.04). In regard to the TS intensity, no significant difference was observed up to 48 hours after in-office bleaching (p=0.09) and during the at-home bleaching phase of the study (p=0.71).
The combined bleaching technique using at-home bleaching associated with in-office bleaching was effective and stable over the course of 12 months, regardless of the concentration of the hydrogen peroxide used for in-office bleaching. However, the protocol with 20% hydrogen peroxide produced lower risk and intensity of TS.
本研究旨在评估采用20%或35%过氧化氢进行诊室美白方案的联合漂白技术的疗效、颜色稳定性、牙齿敏感(TS)风险及强度。
30例患者随机分为两组,分别接受一次45分钟的诊室漂白治疗,一组使用35%过氧化氢,另一组使用20%过氧化氢。家庭漂白使用10%过氧化脲,每天进行2小时,持续两周。在漂白后长达12个月的不同时间段,使用Vita经典比色板以明度为导向评估颜色。患者使用五点语言量表记录TS强度。颜色变化数据进行双向重复测量方差分析和Tukey检验(α=0.05)。TS的绝对风险和强度分别采用Fisher精确检验和Mann-Whitney检验进行比较(α=0.05)。
平均而言,两组在比色板上均观察到有效且相似的三个色阶美白效果,且在12个月内保持稳定。比较两种方案时,使用35%过氧化氢的方案显示出更高的TS风险(p=0.02)和强度(p=0.04)。关于TS强度,在诊室漂白后48小时内(p=0.09)以及研究的家庭漂白阶段(p=0.71)均未观察到显著差异。
无论诊室漂白所用过氧化氢的浓度如何,家庭漂白与诊室漂白相结合的联合漂白技术在12个月内均有效且稳定。然而,使用20%过氧化氢的方案产生的TS风险和强度较低。