IgA肾病中的免疫调节
Immune regulation in IgA nephropathy.
作者信息
Monteiro R C, Noël L H, Chevailler A, Halbwachs-Mecarelli L, Lesavre P
机构信息
Département de Néphrologie et INSERM U 25, Hôpital Necker, Paris.
出版信息
Nephrologie. 1989;10(3):147-50.
PMID:2691912
Abstract
Regulation in IgA nephropathy (IgA N) has been largely studied. We present in this work our recent data which suggest that an abnormal chemical structure and/or molecular form of serum immunoglobulin A (IgA) might contribute to both the mesangial deposition of IgA and the T cell abnormalities which may in turn deregulate the IgA synthesis.
摘要
对IgA肾病（IgA N）的调控已进行了大量研究。在这项工作中，我们展示了我们最近的数据，这些数据表明血清免疫球蛋白A（IgA）异常的化学结构和/或分子形式可能导致IgA在系膜沉积以及T细胞异常，而T细胞异常反过来可能会使IgA合成失调。
相似文献
1
Immune regulation in IgA nephropathy.
Nephrologie. 1989;10(3):147-50.
2
New insights in the pathogenesis of IgA nephropathy.
Nefrologia. 2005;25 Suppl 2:82-6.
3
Immunopathogenetic aspects of IgA nephropathy.
Nephrologie. 1989;10(3):141-5.
4
[Immunopathogenesis of IgA nephropathy--new data based on the clinical and experimental studies].
Przegl Lek. 1992;49(1-2):13-5.
5
IgA-CD89 complex in IgA nephropathy: a study on molecular function.
Ren Fail. 2006;28(6):457-9. doi: 10.1080/08860220600767327.
6
Detection and characterization of circulating and glomerular immune complexes in experimental IgA nephropathy.
Immunology. 1990 Jul;70(3):296-302.
7
[New immunopathogenic aspects of IgA nephropathy].
Bull Acad Natl Med. 1990 May;174(5):549-59.
8
Pathogenesis of IgA nephropathy: in vitro activation of human mesangial cells by IgA immune complex leads to cytokine secretion.
J Pathol. 1994 Jun;173(2):119-26. doi: 10.1002/path.1711730208.
9
[The pathogenesis of primary IgA-nephropathy].
Tijdschr Kindergeneeskd. 1990 Apr;58(2):55-9.
10
[Pathogenesis of Berger's disease: recent advances on the involvement of immunoglobulin A and their receptors].
Med Sci (Paris). 2003 Dec;19(12):1233-41. doi: 10.1051/medsci/200319121233.
Zotero 插件