Monteiro R C, Noël L H, Chevailler A, Halbwachs-Mecarelli L, Lesavre P
Département de Néphrologie et INSERM U 25, Hôpital Necker, Paris.
Nephrologie. 1989;10(3):147-50.
Regulation in IgA nephropathy (IgA N) has been largely studied. We present in this work our recent data which suggest that an abnormal chemical structure and/or molecular form of serum immunoglobulin A (IgA) might contribute to both the mesangial deposition of IgA and the T cell abnormalities which may in turn deregulate the IgA synthesis.
对IgA肾病（IgA N）的调控已进行了大量研究。在这项工作中，我们展示了我们最近的数据，这些数据表明血清免疫球蛋白A（IgA）异常的化学结构和/或分子形式可能导致IgA在系膜沉积以及T细胞异常，而T细胞异常反过来可能会使IgA合成失调。
