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人类真菌病原体:我们为何要了解?

Human fungal pathogens: Why should we learn?

作者信息

Kim Jeong-Yoon

机构信息

Department of Microbiology and Molecular Biology, College of Bioscience and Biotechnology, Chungnam National University, Daejeon, 34134, Republic of Korea.

出版信息

J Microbiol. 2016 Mar;54(3):145-8. doi: 10.1007/s12275-016-0647-8.

Abstract

Human fungal pathogens that cause invasive infections are hidden killers, taking lives of one and a half million people every year. However, research progress in this field has not been rapid enough to effectively prevent or treat life-threatening fungal diseases. To update recent research progress and promote more active research in the field of human fungal pathogens, eleven review articles concerning the virulence mechanisms and host interactions of four major human fungal pathogens-Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus, and Histoplasma capsulatum-are presented in this special issue.

摘要

引发侵袭性感染的人类真菌病原体是隐藏的杀手,每年导致150万人死亡。然而,该领域的研究进展不够迅速,无法有效预防或治疗危及生命的真菌疾病。为了更新近期的研究进展并推动在人类真菌病原体领域开展更积极的研究,本期特刊发表了11篇综述文章,内容涉及四种主要人类真菌病原体——白色念珠菌、新型隐球菌、烟曲霉和荚膜组织胞浆菌的致病机制及与宿主的相互作用。

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