Rodríguez-Cintas Laia, Daigre Constanza, Grau-López Lara, Barral Carmen, Pérez-Pazos Jesús, Voltes Núria, Braquehais María Dolores, Casas Miquel, Roncero Carlos
Addiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d'Hebron University Hospital - Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
Addiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d'Hebron University Hospital - Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
Addict Behav. 2016 Jul;58:104-9. doi: 10.1016/j.addbeh.2016.02.029. Epub 2016 Feb 17.
Impulsivity as a personality trait is a risk factor for the development and maintenance of cocaine and opioid dependence. The objective of this study is to analyze the relationship between impulsivity and addiction severity in cocaine and opioid dependent patients.
A cross-sectional, observational study of 526 patients with lifetime cocaine dependence (CD, n=351), opiate dependence (OD, n=51) and comorbid cocaine and opiate dependence (COD, n=124) to throughout life, according to DSM-IV-TR, was conducted. The sample was recruited at the Addiction and Dual Diagnosis Unit of Vall d'Hebron University Hospital from January 2006 to April 2013. Patients were evaluated with the EuropASI, the SCID I and II interviews, and the Barratt Impulsivity Scale (BIS-11). Descriptive statistics of the main variables (including mean, standard deviation) was performed. Chi square test was used to compare categorical variables and Kruskal-Wallis test to compare continuous variables. Spearman correlation was used to analyze the relationship between EuropASI scores and BIS-11 scores.
The mean age of the patients was 36.37years±8.08 (19-66). CD and COD were more impulsive and had higher addiction severity than OD. OD patients had worse medical status than CD and COD patients while COD patients had more severe drug use and legal problems than the other groups. However, impulsivity and addiction severity were only positively correlated in CD patients.
Impulsivity should be appropriately screened and addressed in cocaine dependents as it may be related to addiction severity.
冲动作为一种人格特质，是可卡因和阿片类药物依赖发展及维持的一个风险因素。本研究的目的是分析可卡因和阿片类药物依赖患者中冲动与成瘾严重程度之间的关系。
根据《精神疾病诊断与统计手册》第四版修订版（DSM-IV-TR），对526例终生患有可卡因依赖（CD，n = 351）、阿片类药物依赖（OD，n = 51）以及可卡因和阿片类药物共病依赖（COD，n = 124）的患者进行了一项横断面观察性研究。样本于2006年1月至2013年4月在瓦尔德希伯伦大学医院成瘾与双重诊断科招募。患者接受了欧洲成瘾严重程度指数（EuropASI）、《精神疾病诊断与统计手册》第一版和第二版访谈以及巴拉特冲动性量表（BIS-11）评估。对主要变量进行了描述性统计（包括均值、标准差）。采用卡方检验比较分类变量，采用克鲁斯卡尔-沃利斯检验比较连续变量。使用斯皮尔曼相关性分析EuropASI评分与BIS-11评分之间的关系。
患者的平均年龄为36.37岁±8.08（19 - 66岁）。与OD患者相比，CD和COD患者更冲动，成瘾严重程度更高。OD患者的健康状况比CD和COD患者差，而COD患者的药物使用和法律问题比其他组更严重。然而，冲动与成瘾严重程度仅在CD患者中呈正相关。
应对可卡因依赖者进行冲动性的适当筛查和处理，因为它可能与成瘾严重程度有关。
