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减重手术前的体重减轻及其对 2 年时不良与良好结局的影响。

Weight loss before bariatric surgery and its impact on poor versus excellent outcomes at 2 years.

机构信息

The Obesity Clinic at Hospital General Tláhuac, Avenida la Turba # 655, Col. Villa Centroamericana y del Caribe, Delegación Tláhuac, 13250, México City, Mexico.

出版信息

Langenbecks Arch Surg. 2022 May;407(3):1047-1053. doi: 10.1007/s00423-021-02399-z. Epub 2022 Jan 11.

Abstract

PURPOSE

To identify preoperative factors that influence the outcomes of gastric bypass surgery, in terms of excess weight loss at 24 months.

METHODS

This retrospective study included two groups of patients who underwent laparoscopic gastric bypass surgery. Group A (poor outcomes) had ≤ 50%EWL or BMI ≥ 30 kg/m; group B (excellent outcomes) had ≥ 80%EWL at 24 months. A comparative analysis of demography, anthropometry, comorbidities, and metabolic status was performed. A linear regression model was used to evaluate %EWL association; the number of preoperative and postoperative consultations were also compared.

RESULTS

A total of 202 patients completed follow-up; 71 (35.1%) and 78 (38%) had poor and excellent outcomes (%EWL 44.1 ± 9.4% vs. 92 ± 10.9%), respectively. Mean age was 40.4 ± 8.9 years. Patients with poor outcomes had higher weight and BMI, lesser preoperative %EWL, higher dyslipidemia and diabetes rates with longer periods of evolution, and increased HbA1c% levels. In the linear regression analysis, preoperative %EWL and initial and preoperative BMI were statistically significant determinants of %EWL at 24 months Diabetes remission was 46.2% (group A) vs. 66.6% (group B). Group A had higher non-attendance rates after surgery.

CONCLUSION

The factors independently associated with greater %EWL at 24 months between groups were higher preoperative %EWL, and lower initial and preoperative BMI.

摘要

目的

确定影响胃旁路手术结果的术前因素,以 24 个月时的超重减轻率为衡量标准。

方法

本回顾性研究纳入两组接受腹腔镜胃旁路手术的患者。A 组(不良结果)的超重减轻率(EWL)≤50%或 BMI≥30kg/m;B 组(良好结果)的 EWL 在 24 个月时≥80%。对两组患者的人口统计学、人体测量学、合并症和代谢状况进行了对比分析。采用线性回归模型评估 EWL 相关性;比较了术前和术后的就诊次数。

结果

共 202 例患者完成随访;71 例(35.1%)和 78 例(38%)患者的结果为不良和良好(EWL 分别为 44.1±9.4%和 92±10.9%)。患者平均年龄为 40.4±8.9 岁。不良结果组的体重和 BMI 更高,术前 EWL 较低,血脂异常和糖尿病的发生率更高,病程更长,HbA1c%水平更高。线性回归分析表明,术前 EWL、初始 BMI 和术前 BMI 是 24 个月时 EWL 的统计学显著决定因素。糖尿病缓解率为 46.2%(A 组)和 66.6%(B 组)。A 组患者术后的失访率更高。

结论

与两组间 24 个月时更高 EWL 相关的独立因素为术前 EWL 更高,以及初始 BMI 和术前 BMI 更低。

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