Gottrup F, Gjøde P, Lundhus E, Andrup H, Holm C N, Terpling S
Ugeskr Laeger. 1989 Dec 18;151(51):3486-7.
A randomized double-blind investigation was undertaken to assess the effect of treatment with metronidazole and ampicillin in patients with subcutaneous wound infection after laparotomy and early resuture. The wounds were closed in the fourth day and the antibiotic cover lasted from one to four days. None of the patients developed signs of sepsis or new abscesses. All of the wounds healed primarily but there were slight defects in two patients. These did not require surgical treatment. It is concluded that early closure of infected wounds after laparotomy may be undertaken under metronidazole and ampicillin cover and that treatment for one day is sufficient.
进行了一项随机双盲研究，以评估甲硝唑和氨苄西林治疗剖腹术后皮下伤口感染并早期重新缝合患者的效果。伤口在第四天闭合，抗生素覆盖持续一至四天。所有患者均未出现败血症或新脓肿的迹象。所有伤口均一期愈合，但有两名患者存在轻微缺损。这些缺损无需手术治疗。结论是，剖腹术后感染伤口可在甲硝唑和氨苄西林覆盖下早期闭合，且治疗一天就足够了。
