Akar Tarık, Dindar Gökhan, Malkoç Dilek, Karagözoğlu Kemal, Kılavuz Beyza, Üstündağ Yücel
Gastroenterology Department, School of Medicine, Bulent Ecevit University, Zonguldak, Turkey.
Internal Medicine, School of Medicine, Bulent Ecevit University, Zonguldak, Turkey.
Arch Iran Med. 2016 Mar;19(3):225-8.
Chronic abdominal pain sometimes constitute a major challenge, specially when a patient has two diseases with dominant features of abdominal pain in both. At this point, clinicians face a daunting task both in diagnosing and treating an individual's chronic abdominal pain. Similarly, familial Mediterranean fever disease and Crohn's disease have the same clinical features in terms of chronic abdominal pain, and inflammatory properties of these diseases. The association of familial Mediterranean fever disease and Crohn's disease is very rare and may lead to a remarkable challenge in both diagnosis and treatment. Here, we report a young man with FMF disease presented with extraordinary and intolerable abdominal pain relieved only by excessive narcotic analgesics. The presented case was diagnosed with CD and successfully treated with anti-TNF (tumor necrosis factor) due to steroid refractory.
慢性腹痛有时会构成一项重大挑战，尤其是当患者患有两种都以腹痛为主要特征的疾病时。此时，临床医生在诊断和治疗个体的慢性腹痛方面面临艰巨任务。同样，家族性地中海热疾病和克罗恩病在慢性腹痛以及这些疾病的炎症特性方面具有相同的临床特征。家族性地中海热疾病与克罗恩病的关联非常罕见，可能在诊断和治疗方面都带来显著挑战。在此，我们报告一名患有家族性地中海热疾病的年轻男子，其腹痛异常且难以忍受，只有通过大量麻醉性镇痛药才能缓解。该病例被诊断为克罗恩病，由于对类固醇耐药，最终通过抗TNF（肿瘤坏死因子）治疗成功治愈。
