Griffith David C, Adler David, Wallace Melissa, Bennie Thola, Abar Beau, Bekker Linda-Gail
Department of Internal Medicine and Pediatrics, University of Rochester, Rochester NY, USA.
601 Elmwood Avenue, Box 655, Department of Emergency Medicine, University of Rochester, Rochester, NY, 14534, USA.
J Womens Health Issues Care. 2015;4(5). doi: 10.4172/2325-9795.1000203. Epub 2015 Sep 23.
The aim of this study is to examine the knowledge of human papillomavirus (HPV) and cervical cancer among HIV-infected and HIV-uninfected female adolescents in South Africa.
Subjects were recruited from a parent study of HPV infection comprised of females ages 16-21 in Masiphumelele, Cape Town, South Africa. A total of 30 subjects, 15 HIV-infected and 15 HIV-uninfected, were selected via randomization and completed a measure of HPV knowledge, based on a previously validated instrument. The study took place in May 2013.
The overall mean score on the measure for all subjects was 43.3% (S.D. 10.9). There was no significant difference in HPV knowledge between the HIV-infected and HIV-uninfected groups. Based on results from a previous large-scale study using the same validated measure, this sample scored significantly worse on general HPV knowledge than samples from the US, UK, and Australia.
Given the limited knowledge of HPV in this sample, there is greater need for education about the prevention of cervical cancer, specifically among high-risk adolescent women.
本研究旨在调查南非感染人类免疫缺陷病毒（HIV）和未感染HIV的女性青少年对人乳头瘤病毒（HPV）和宫颈癌的了解情况。
研究对象来自南非开普敦马西富梅莱勒一项关于HPV感染的母研究，该研究涵盖16至21岁的女性。通过随机抽样，共选取了30名受试者，其中15名感染HIV，15名未感染HIV。她们基于一份先前经验证有效的工具，完成了一项HPV知识测试。该研究于2013年5月开展。
所有受试者的测试总体平均得分为43.3%（标准差为10.9）。感染HIV组和未感染HIV组在HPV知识方面无显著差异。根据此前一项使用相同经验证测试的大规模研究结果，该样本在HPV总体知识方面的得分显著低于来自美国、英国和澳大利亚的样本。
鉴于该样本对HPV的了解有限，对于预防宫颈癌的教育，尤其是针对高危青少年女性的教育，有更大的需求。
