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Breath Testing for Small Intestinal Bacterial Overgrowth: A Means to Enrich Rifaximin Responders in IBS Patients?

作者信息

Gupta Amit, Chey William D

机构信息

Department of Internal Medicine, Division of Gastroenterology, University of Michigan Health System, Ann Arbor, Michigan, USA.

出版信息

Am J Gastroenterol. 2016 Mar;111(3):305-6. doi: 10.1038/ajg.2016.32. Epub 2016 Mar 1.

DOI:10.1038/ajg.2016.32
PMID:26925880
Abstract
摘要

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A study of the methodological and clinical validity of the combined lactulose hydrogen breath test with scintigraphic oro-cecal transit test for diagnosing small intestinal bacterial overgrowth in IBS patients.一项关于联合使用乳果糖氢呼气试验与闪烁扫描法口盲肠转运试验诊断肠易激综合征（IBS）患者小肠细菌过度生长的方法学及临床有效性的研究。
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Small intestinal bacterial overgrowth produces symptoms in irritable bowel syndrome which are improved by rifaximin. A pilot study.小肠细菌过度生长在肠易激综合征中产生症状，利福昔明可改善这些症状。一项初步研究。
Rom J Intern Med. 2013 Jul-Dec;51(3-4):143-7.
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Value-based Pricing for Rifaximin Increases Access of Patients With Irritable Bowel Syndrome With Diarrhea to Therapy.

本文引用的文献

1
Breath testing for small intestinal bacterial overgrowth: maximizing test accuracy.小肠细菌过度生长的呼吸试验：最大限度提高试验准确性。
Clin Gastroenterol Hepatol. 2014 Dec;12(12):1964-72; quiz e119-20. doi: 10.1016/j.cgh.2013.09.055. Epub 2013 Oct 1.
2
The efficacy and safety of rifaximin for the irritable bowel syndrome: a systematic review and meta-analysis.利福昔明治疗肠易激综合征的疗效和安全性：系统评价和荟萃分析。
Am J Gastroenterol. 2012 Jan;107(1):28-35; quiz 36. doi: 10.1038/ajg.2011.355. Epub 2011 Nov 1.
3
Rifaximin therapy for patients with irritable bowel syndrome without constipation.
利福昔明基于价值的定价增加了腹泻型肠易激综合征患者获得治疗的机会。
Clin Gastroenterol Hepatol. 2019 Dec;17(13):2687-2695.e11. doi: 10.1016/j.cgh.2019.02.039. Epub 2019 Mar 1.
4
The gut microbiome and irritable bowel syndrome.肠道微生物群与肠易激综合征
F1000Res. 2018 Jul 9;7. doi: 10.12688/f1000research.14592.1. eCollection 2018.
5
Systematic review with meta-analysis: rifaximin is effective and safe for the treatment of small intestine bacterial overgrowth.系统评价与荟萃分析：利福昔明治疗小肠细菌过度生长有效且安全。
Aliment Pharmacol Ther. 2017 Mar;45(5):604-616. doi: 10.1111/apt.13928. Epub 2017 Jan 12.
6
Therapeutic Modulation of Gut Microbiota in Functional Bowel Disorders.功能性肠病中肠道微生物群的治疗性调节
J Neurogastroenterol Motil. 2017 Jan 30;23(1):9-19. doi: 10.5056/jnm16124.
7
It is Time to Re-Think the Role of Small Intestinal Bacterial Overgrowth in IBS Patients.是时候重新思考小肠细菌过度生长在肠易激综合征患者中的作用了。
Am J Gastroenterol. 2016 Sep;111(9):1364. doi: 10.1038/ajg.2016.290.
8
Use of rifaximin in gastrointestinal and liver diseases.利福昔明在胃肠道和肝脏疾病中的应用。
World J Gastroenterol. 2016 Aug 7;22(29):6638-51. doi: 10.3748/wjg.v22.i29.6638.
利福昔明治疗无便秘型肠易激综合征患者。
N Engl J Med. 2011 Jan 6;364(1):22-32. doi: 10.1056/NEJMoa1004409.
4
Rifaximin: a unique gastrointestinal-selective antibiotic for enteric diseases.利福昔明：一种用于治疗肠道疾病的胃肠道选择性抗生素。
Curr Opin Gastroenterol. 2010 Jan;26(1):17-25. doi: 10.1097/MOG.0b013e328333dc8d.
5
Methodology and indications of H2-breath testing in gastrointestinal diseases: the Rome Consensus Conference.胃肠疾病中H2呼气试验的方法与指征：罗马共识会议
Aliment Pharmacol Ther. 2009 Mar 30;29 Suppl 1:1-49. doi: 10.1111/j.1365-2036.2009.03951.x.