Lee Hyo Jeong, Choi Jong Kyoung, Ryu Han Seung, Choi Chang Hwan, Kang Eun Hee, Park Kyung Sik, Min Yang Won, Hong Kyoung Sup
Health Screening and Promotion Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Department of Internal Medicine, National Medical Center, Seoul, Korea.
J Neurogastroenterol Motil. 2017 Jan 30;23(1):9-19. doi: 10.5056/jnm16124.
Functional bowel disorders (FBDs) are functional gastrointestinal disorders with symptoms attributable to the middle or lower gastrointestinal tract. These include irritable bowel syndrome, functional bloating, functional constipation, functional diarrhea, and unspecified FBD. Increasing evidence has emerged of late that intestinal microbiota is involved in the pathogenesis of FBDs. In this review, the therapeutic benefits and future perspectives of the currently available strategies for modifying the gut microbiota in FBDs are described, focusing primarily on irritable bowel syndrome and functional constipation.
功能性肠病（FBDs）是一类功能性胃肠疾病，其症状归因于中、下消化道。这些疾病包括肠易激综合征、功能性腹胀、功能性便秘、功能性腹泻以及未特定的功能性肠病。近来，越来越多的证据表明肠道微生物群参与了功能性肠病的发病机制。在本综述中，描述了目前用于改变功能性肠病肠道微生物群的策略的治疗益处和未来前景，主要聚焦于肠易激综合征和功能性便秘。
