Wang Jing, Li Guangyu, Zhong Wei, Zhang Haihua, Yang Qianlong, Chen Lihong, Wang Jinming, Yang Xuewen
Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, China.
College of Animal Science and Technology, Qingdao Agriculture University, Qingdao, China.
Front Vet Sci. 2022 Apr 4;9:839450. doi: 10.3389/fvets.2022.839450. eCollection 2022.
Paeoniae radix alba extract (PRA extract) has the functions of regulating immunity, resisting inflammation, and has antioxidant properties. However, current recommendations of dietary PRA extract levels for raccoon dogs were inadequate. The purpose of this experimental study was to gain information allowing for better estimating the effects of PRA extract on raccoon dogs, and their PRA requirements. Fifty healthy male raccoon dogs of (120 ± 5) days old were randomly divided into 5 groups (group PRA0, PRA1, PRA2, PRA4, PRA8) with 10 animals in each group and 1 in each replicate. Five kinds of experimental diets were prepared with five levels of Paeoniae radix alba extract (0, 1, 2, 4, 8 g/kg) in the basic diet. The prefeeding period was 7 days and the experimental period was 40 days. The results showed that the average daily feed intake in group PRA1 and PRA2 was significantly higher than that in other groups ( < 0.01). The dry matter excretion in group PRA8 was significantly higher than that in other groups ( < 0.01), while the dry matter digestibility and protein digestibility in group PRA8 were significantly lower than those in other groups ( < 0.01). Nitrogen retention in group PRA1 and PRA2 was significantly higher than that in group PRA8 ( < 0.05). With the increase of the content of Paeoniae radix alba extract in diet, the activity of alkaline phosphatase in group PRA2 was significantly higher than that in group PRA0 ( < 0.05); The activity of serum SOD in group PRA4 was significantly higher than that in other groups ( < 0.01). The content of serum IgA in group PRA2 was significantly higher than that in other groups ( < 0.05). The content of TNF-α in intestinal mucosa in group PRA1 and group PRA2 was significantly lower than that in group PRA0 ( < 0.05). In conclusion, we found that dietary Paeoniae radix alba extract intake significantly improved the feed intake and nitrogen deposition of Ussuri raccoon dog, increased the content of serum IgA and reduced the content of TNF-α in the small intestinal mucosa. We suggest that an estimated dietary Paeoniae radix alba extract level of 1 to 2 g/kg could be used as a guide to achieve the optimal performance of raccoon dogs.
白芍提取物（PRA提取物）具有调节免疫、抗炎以及抗氧化特性。然而，目前关于貉日粮中PRA提取物水平的建议并不充分。本实验研究的目的是获取信息，以便更好地评估PRA提取物对貉的影响及其对PRA的需求。将50只健康的（120±5）日龄雄性貉随机分为5组（PRA0组、PRA1组、PRA2组、PRA4组、PRA8组），每组10只，每个重复1只。在基础日粮中添加5个水平（0、1、2、4、8 g/kg）的白芍提取物，配制5种实验日粮。预饲期为7天，实验期为40天。结果表明，PRA1组和PRA2组的平均日采食量显著高于其他组（P<0.01）。PRA8组的干物质排泄量显著高于其他组（P<0.01），而PRA8组的干物质消化率和蛋白质消化率显著低于其他组（P<0.01）。PRA1组和PRA2组的氮保留量显著高于PRA8组（P<0.05）。随着日粮中白芍提取物含量的增加，PRA2组碱性磷酸酶活性显著高于PRA0组（P<0.05）；PRA4组血清超氧化物歧化酶活性显著高于其他组（P<0.01）。PRA2组血清IgA含量显著高于其他组（P<0.05）。PRA1组和PRA2组小肠黏膜中TNF-α含量显著低于PRA0组（P<0.05）。综上所述，我们发现日粮中添加白芍提取物显著提高了乌苏里貉的采食量和氮沉积，增加了血清IgA含量，降低了小肠黏膜中TNF-α含量。我们建议日粮中白芍提取物的估计水平为1至2 g/kg，可作为实现貉最佳生产性能的指导。
