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动态颈椎植入物置换术与颈椎全椎间盘置换术治疗单节段颈椎退行性椎间盘疾病的临床及影像学比较

Clinical and radiologic comparison of dynamic cervical implant arthroplasty and cervical total disc replacement for single-level cervical degenerative disc disease.

作者信息

Shichang Liu, Yueming Song, Limin Liu, Lei Wang, Zhongjie Zhou, Chunguang Zhou, Xi Yang

机构信息

Department of Orthopedics, West China Hospital of Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan 610041, China.

Department of Orthopedics, West China Hospital of Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan 610041, China.

出版信息

J Clin Neurosci. 2016 May;27:102-9. doi: 10.1016/j.jocn.2015.05.072. Epub 2016 Feb 28.

Abstract

Anterior cervical discectomy and fusion, to date the most successful spine procedure for the surgical treatment of cervical radiculopathy, has limitations that have led to the development of non-fusion cervical procedures, such as cervical total disc replacement (TDR) and dynamic cervical implant (DCI) arthroplasty. We compared the clinical and radiological results of DCI and cervical TDR for the treatment of single-level cervical degenerative disc disease in Chinese patients. A retrospective review of 179 patients with cervical spondylotic myelopathy who underwent DCI or TDR between April 2010 and October 2012 was conducted, and 152 consecutive patients (67 patients single-level DCI and 85 single-level TDR) who completed at least 2years of follow-up were included. Clinical and radiological assessments were performed preoperatively and at 1week and 3, 6, 12, and 24months postoperatively. The most common operative level was C5/C6 (49.3%). The differences in blood loss, duration of surgery, and duration of hospitalization were not statistically significant. The Japanese Orthopaedic Association scale, Visual Analog Scale, Neck Disability Index, and Short Form-36 scores improved significantly after surgery in both the DCI and TDR groups (P<0.05), but the differences were not statistically significant at the final follow-up. The rate of occurrence of heterotopic ossification was 22.4% and 28.2% in the DCI and TDR groups, respectively. As an effective non-fusion technique, DCI is a more economical procedure. Further prospective, randomized studies with long-term follow-up periods are needed to determine the long-term effects.

摘要

颈椎前路椎间盘切除融合术是迄今为止治疗神经根型颈椎病最成功的脊柱手术,但该手术存在局限性,这促使了非融合颈椎手术的发展,如颈椎全椎间盘置换术(TDR)和动力性颈椎植入物(DCI)关节成形术。我们比较了DCI和颈椎TDR治疗中国患者单节段颈椎退行性椎间盘疾病的临床和影像学结果。对2010年4月至2012年10月期间接受DCI或TDR治疗的179例脊髓型颈椎病患者进行了回顾性研究,纳入了152例连续完成至少2年随访的患者(67例单节段DCI和85例单节段TDR)。在术前、术后1周、3、6、12和24个月进行临床和影像学评估。最常见的手术节段是C5/C6(49.3%)。出血量、手术时间和住院时间的差异无统计学意义。DCI组和TDR组术后日本骨科协会评分、视觉模拟评分、颈部功能障碍指数和简明健康状况调查-36评分均显著改善(P<0.05),但在末次随访时差异无统计学意义。DCI组和TDR组异位骨化发生率分别为22.4%和28.2%。作为一种有效的非融合技术,DCI是一种更经济的手术方式。需要进一步进行长期随访的前瞻性随机研究以确定其长期效果。

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