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动态颈椎植入物(DCI)置换术治疗退行性颈椎间盘疾病的临床及影像学结果:至少五年随访

Clinical and radiographic outcome of dynamic cervical implant (DCI) arthroplasty for degenerative cervical disc disease: a minimal five-year follow-up.

作者信息

Wang Lin-Nan, Hu Bo-Wen, Wang Lei, Song Yue-Ming, Yang Xi, Liu Li-Min, Liu Hao

机构信息

Department of Orthopedics, West China Hospital, Sichuan University, 37 Guoxue Rd, Chengdu, 610041, China.

出版信息

BMC Musculoskelet Disord. 2018 Apr 4;19(1):101. doi: 10.1186/s12891-018-2017-7.

Abstract

BACKGROUND

To evaluate the mid- to long-term clinical and radiographic outcomes of anterior cervical discectomy and dynamic cervical implant (DCI) arthroplasty for degenerative cervical disc disease.

METHODS

From April 2010 to October 2010, 38 patients with single- or double-level cervical disc herniation underwent anterior cervical discectomy and DCI arthroplasty. The clinical results and radiographic outcomes of these 38 patients (42 levels) were retrospectively evaluated. The clinical results included the visual analogue scale, Japanese Orthopaedic Association score, Neck Disability Index score, 36-item short form health survey questionnaire, and incidences of complications and neurological deterioration. Radiographic results including cervical alignment, intervertebral height, cervical range of motion (ROM), ROM of the functional spinal unit, adjacent intervertebral ROM, migration, subsidence, and heterotopic ossification (HO) were assessed on plain radiography, three-dimensional computed tomography, and magnetic resonance imaging.

RESULTS

The mean follow-up period was 72.3 months (range 68-78 months). During follow-up, all patients showed significant improvements in the visual analogue scale score, Japanese Orthopaedic Association score, Neck Disability Index score, 36-item short form health survey physical component summary score and mental component summary score. The ROM of the functional spinal unit was partly reduced. The DCI migrated forward in 10 of 42 (23.8%) cases, and HO was detected in 24 of the 42 (57.1%) DCI segments. Subsidence was observed in 14 of 42 (33.3%) DCI segments. Two patients experienced symptom recurrence, and were treated conservatively.

CONCLUSIONS

The clinical efficacy of DCI arthroplasty was maintained during mid- to long-term follow-up. HO formation is a common phenomenon, leading to a substantial decrease in ROM at the index level and recurrence of neurological symptoms. The incidence of implant subsidence and migration is relatively high, leaving a potential risk of symptoms at the index level and adjacent segment degeneration. We consider that the first choice for patients with degenerative cervical disc disease should still be total disc replacement or anterior cervical discectomy and fusion, rather than DCI arthroplasty.

摘要

背景

评估颈椎前路椎间盘切除联合动力型颈椎椎间融合器(DCI)置换术治疗退变性颈椎间盘疾病的中长期临床及影像学疗效。

方法

2010年4月至2010年10月,38例单节段或双节段颈椎间盘突出症患者接受了颈椎前路椎间盘切除及DCI置换术。对这38例患者(42个节段)的临床结果及影像学疗效进行回顾性评估。临床结果包括视觉模拟评分、日本骨科协会评分、颈部功能障碍指数评分、36项简明健康调查问卷,以及并发症和神经功能恶化的发生率。影像学结果包括颈椎排列、椎间高度、颈椎活动度(ROM)、功能性脊柱单元的ROM、相邻节段的ROM、移位、下沉及异位骨化(HO),通过X线平片、三维计算机断层扫描及磁共振成像进行评估。

结果

平均随访时间为72.3个月(范围68 - 78个月)。随访期间,所有患者的视觉模拟评分、日本骨科协会评分、颈部功能障碍指数评分、36项简明健康调查问卷的身体成分总结评分及精神成分总结评分均有显著改善。功能性脊柱单元的ROM部分降低。42个节段中有10个(23.8%)出现DCI向前移位,42个DCI节段中有24个(57.1%)检测到HO。42个DCI节段中有14个(33.3%)观察到下沉。2例患者症状复发,接受了保守治疗。

结论

DCI置换术的临床疗效在中长期随访中得以维持。HO形成是一种常见现象,导致手术节段的ROM大幅下降及神经症状复发。植入物下沉和移位的发生率相对较高,存在手术节段症状及相邻节段退变的潜在风险。我们认为,退变性颈椎间盘疾病患者的首选治疗方法仍应是全椎间盘置换或颈椎前路椎间盘切除融合术,而非DCI置换术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed0/5883531/e8d1e159733f/12891_2018_2017_Fig1_HTML.jpg

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