Dipartimento di Scienze Mediche - Sezione di Dermatologia e Malattie Infettive, University of Ferrara, 44100, Ferrara, Italy.
Contact Dermatitis. 2016 May;74(5):289-94. doi: 10.1111/cod.12559. Epub 2016 Feb 29.
Topical remedies based on botanical ingredients are popular.
To assess: (i) the usage of botanical substances in subjects affected with itching and chronic vulvar complaints; (ii) the incidence of side-effects associated with their use and the frequency of contact allergy; (iii) the diagnostic usefulness of patch testing.
Sixty-six patients were provided with a questionnaire to assess the prevalence and type of topical botanical preparations used and the occurrence of adverse reactions. Patients were patch tested with (i) the Italian baseline series, (ii) a topical medicament series, and (iii) a botanical series.
Forty-two patients (63.6%) reported the use of natural topical products on the vulva. Seven (16.7%) noted adverse reactions; 27 showed positive reactions with the baseline series; 14 (21.2%) had at least one relevant reaction, mainly to allergens in topical products and cosmetics; and 2 (3%) showed positive reactions to the botanical series. Of the 7 patients complaining of adverse effects of botanical products, 3 (42.8%) showed relevant sensitization.
The use of natural topical products is widespread among women affected with itching vulvar diseases. Contact dermatitis is a possible adverse effect. Botanical series are of questionable usefulness, owing to the wide variety of botanical ingredients.
基于植物成分的局部治疗方法很受欢迎。
评估：（i）患有瘙痒和慢性外阴疾病的患者中使用植物物质的情况；（ii）与使用相关的副作用发生率和接触过敏的频率；（iii）斑贴试验的诊断价值。
为 66 名患者提供了一份问卷，以评估局部使用植物制剂的流行情况和类型，以及不良反应的发生情况。患者接受了（i）意大利基本系列、（ii）局部药物系列和（iii）植物系列的斑贴试验。
42 名患者（63.6%）报告在外阴使用天然局部产品。7 名患者（16.7%）注意到不良反应；27 名患者对基本系列呈阳性反应；14 名患者（21.2%）至少有一种相关反应，主要是对局部产品和化妆品中的变应原过敏；2 名患者（3%）对植物系列呈阳性反应。在 7 名抱怨植物产品不良反应的患者中，有 3 名（42.8%）显示出相关致敏。
在患有瘙痒性外阴疾病的女性中，广泛使用天然局部产品。接触性皮炎是一种可能的不良反应。由于植物成分种类繁多，植物系列的用途值得怀疑。
