Bauer A, Rodiger C, Greif C, Kaatz M, Elsner P
Department of Dermatology and Allergology, Friedrich Schiller University Jena, Jena, Germany.
Dermatology. 2005;210(2):143-9. doi: 10.1159/000082570.
Irritant and allergic contact dermatitis are commonly seen in patients complaining about itching, burning and irritation in the vulvar area. Irritation often precedes allergic sensitization. Clinically, irritant and allergic contact dermatitis can be difficult to distinguish. Diagnosis is made by history, clinical investigation and patch testing. Recommended patch test series are the standard series, a medicament series, the patient's own topical medicaments, popular remedies and other suspected products. A skin biopsy may be useful to establish the diagnosis of contact dermatitis, but it is usually not helpful for the differential diagnosis between irritant and allergic dermatitis.
刺激性和过敏性接触性皮炎常见于主诉外阴部位瘙痒、灼痛和刺激感的患者。刺激通常先于过敏致敏。临床上,刺激性和过敏性接触性皮炎可能难以区分。通过病史、临床检查和斑贴试验进行诊断。推荐的斑贴试验系列包括标准系列、药物系列、患者自用的局部用药、常用疗法及其他可疑产品。皮肤活检可能有助于确诊接触性皮炎,但通常对区分刺激性和过敏性皮炎的鉴别诊断无帮助。