角膜缘自体移植作为利施上皮性角膜营养不良的一种可能的新治疗方法。
Keratolimbal autograft transplantation as a possible new treatment of Lisch epithelial corneal dystrophy.
作者信息
Celis Sánchez J, Mesa Varona D V, Avendaño Cantos E, López-Romero Moraleda S, Cebrian Rosado E, González Del Valle F
机构信息
Servicio de Oftalmología, Hospital La Mancha Centro, Alcázar de San Juan, Ciudad Real, España.
Servicio de Oftalmología, Hospital La Mancha Centro, Alcázar de San Juan, Ciudad Real, España.
出版信息
Arch Soc Esp Oftalmol. 2016 Jul;91(7):333-6. doi: 10.1016/j.oftal.2016.01.029. Epub 2016 Feb 28.
CASE REPORT
The case concerns 64-year-old woman with visual acuity of 20/40 in the right eye. Slit-lamp examination revealed a grey, feathery corneal opacification with intraepithelial microcysts compatible with Lisch epithelial corneal dystrophy (LECD). It was treated with epithelial debridements, contact lenses and mitomycin C, but the opacification recurred within months. The removal of limbus sector and autologous limbal transplantation (KLAT) were used successfully without recurrence.
CONCLUSIONS
After removal of damaged limbus, KLAT should be considered as a treatment option for asymmetric LECD when other treatments have failed.
病例报告
该病例为一名64岁女性，右眼视力为20/40。裂隙灯检查发现角膜呈灰色、羽毛状混浊，伴有上皮内微囊肿，符合利施上皮性角膜营养不良（LECD）。曾采用上皮清创术、佩戴隐形眼镜和丝裂霉素C进行治疗，但混浊在数月内复发。成功实施了角膜缘扇形切除术和自体角膜缘移植术（KLAT），未再复发。
结论
当其他治疗方法失败后，对于不对称性LECD，在切除受损角膜缘后应考虑采用KLAT作为一种治疗选择。
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