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睫状视网膜动脉阻塞后视网膜结构和功能的保存:一例报告

Preservation of retinal structure and function after cilioretinal artery occlusion: a case report.

作者信息

Brown Craig J

机构信息

The Eye Center, Fayetteville, AR, USA.

出版信息

Int Med Case Rep J. 2016 Feb 11;9:29-34. doi: 10.2147/IMCRJ.S96858. eCollection 2016.

DOI:10.2147/IMCRJ.S96858
PMID:26929671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4755464/
Abstract

Cilioretinal artery occlusion is a cause of sudden, often catastrophic loss of central vision. There are no established effective treatments. Recently, a patient presented 24 hours after a cilioretinal artery occlusion, following a cardiac catheterization prior to which her blood thinners had been discontinued. Lacking an effective way to address the severe retinal ischemic oxidative stress, she was offered, under compassionate use, a multivitamin complex designed to address retinal ischemia and oxidative stress. Significant components of this product are L-methylfolate and n-acetyl cysteine. The patient experienced a rapid unexpected improvement in vision and preservation of retinal structure, suggesting that marked improvement in retinal artery occlusions outcomes may be possible as late as 24 hours postocclusion. This is the third reported case of cilioretinal artery occlusion associated with cardiac catheterization.

摘要

睫状视网膜动脉阻塞是导致突然的、常常是灾难性的中心视力丧失的一个原因。目前尚无已确立的有效治疗方法。最近,一名患者在睫状视网膜动脉阻塞24小时后就诊,该患者此前接受了心脏导管插入术,术前停用了血液稀释剂。由于缺乏有效方法来应对严重的视网膜缺血性氧化应激,在同情用药的情况下,为她提供了一种旨在应对视网膜缺血和氧化应激的多种维生素复合物。该产品的重要成分是L-甲基叶酸和N-乙酰半胱氨酸。患者视力迅速出现意外改善,视网膜结构得以保留,这表明在阻塞后24小时,视网膜动脉阻塞的预后仍有可能显著改善。这是第三例报告的与心脏导管插入术相关的睫状视网膜动脉阻塞病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a78/4755464/57545aca01cb/imcrj-9-029Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a78/4755464/29ee4d7e49ad/imcrj-9-029Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a78/4755464/8304bdc75947/imcrj-9-029Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a78/4755464/57545aca01cb/imcrj-9-029Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a78/4755464/29ee4d7e49ad/imcrj-9-029Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a78/4755464/8304bdc75947/imcrj-9-029Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a78/4755464/57545aca01cb/imcrj-9-029Fig3.jpg

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