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撒哈拉以南非洲地区的心力衰竭:临床诊治方法

Heart failure in sub-Saharan Africa: A clinical approach.

作者信息

Kraus S, Ogunbanjo G, Sliwa K, Ntusi N A B

出版信息

S Afr Med J. 2016 Jan;106(1):23-31. doi: 10.7196/samj.2016.v106i1.10325.

Abstract

Despite medical advances, heart failure (HF) remains a global health problem and sub-Saharan Africa (SSA) is no exception, with decompensated HF being the most common primary diagnosis for patients admitted to hospital with heart disease. In SSA the in-hospital mortality rate of decompensated HF is up to 8.3%. HF is a clinical syndrome that is caused by a diverse group of aetiologies, each requiring unique management strategies, highlighting the need for diagnostic certainty and a broad understanding of the complex pathophysiology of this condition. While there are a number of advanced medical, device and surgical interventions being tailored for HF internationally, the fundamental basic principles of HF management, such as patient education, effective management of congestion and initiation of disease-modifying medical therapies, remain a challenge on our continent. This review addresses both the epidemiology of HF in SSA and principles of management that focus specifically on symptom relief, prevention of hospitalisation and improving survival in this population.

摘要

尽管医学取得了进步,但心力衰竭(HF)仍然是一个全球性的健康问题,撒哈拉以南非洲(SSA)也不例外,失代偿性HF是因心脏病住院患者最常见的主要诊断。在SSA,失代偿性HF的住院死亡率高达8.3%。HF是一种由多种病因引起的临床综合征,每种病因都需要独特的管理策略,这凸显了诊断确定性以及对该疾病复杂病理生理学广泛理解的必要性。虽然国际上有许多针对HF量身定制的先进医疗、器械和外科干预措施,但HF管理的基本原理,如患者教育、有效控制充血以及启动改善病情的药物治疗,在我们这个大陆仍然是一项挑战。本综述探讨了SSA地区HF的流行病学以及专门针对该人群缓解症状、预防住院和提高生存率的管理原则。

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