Könyves I
Pharmacia-LEO Therapeutics AB, Helsingborg, Sweden.
Int Urol Nephrol. 1989;21(4):393-7. doi: 10.1007/BF02559635.
This review presents the most important hormonal, cytotoxic and pharmacokinetic properties of estramustine phosphate. Furthermore the results of randomized Phase III trials are described in patients with hormone refractory prostatic cancer with and without previous irradiation. Several randomized studies are reported with Estracyt also in the primary treatment of this disease.
本综述介绍了磷酸雌莫司汀最重要的激素、细胞毒性和药代动力学特性。此外,还描述了在有或无既往放疗的激素难治性前列腺癌患者中进行的随机III期试验结果。也有几项关于艾去适在该疾病一线治疗中的随机研究报告。