Towbin A
Mental Retardation Research Institute, Danvers, Massachusetts.
J Clin Psychol. 1989 Nov;45(6):910-8. doi: 10.1002/1097-4679(198911)45:6<910::aid-jclp2270450613>3.0.co;2-c.
The present report considers organic factors of pathogenesis, in addition to environmental factors, as causal processes in cases of dual disability of mental retardation and behavior disorders. Relevant to organic pathogenesis, in cases of dual diagnosis, basic biological processes are presented, mechanisms concerned with gestational and birth complications that led to fetal-neonatal hypoxic cerebral cortical damage. In such cases, dual diagnosis manifestations of mental retardation and behavior disorders, together with other chronic cerebral disabilities, may be attributed to residues of fetal-neonatal cerebral damage.
本报告认为，除环境因素外，发病机制中的有机因素也是智力迟钝和行为障碍双重残疾病例的致病过程。与有机发病机制相关的是，在双重诊断病例中，呈现了基本的生物学过程，即与导致胎儿 - 新生儿缺氧性大脑皮质损伤的妊娠和分娩并发症有关的机制。在这些病例中，智力迟钝和行为障碍的双重诊断表现以及其他慢性脑残疾可能归因于胎儿 - 新生儿脑损伤的残留影响。
