Gios Lorenzo, Mirandola Massimo, Toskin Igor, Marcus Ulrich, Dudareva-Vizule Sandra, Sherriff Nigel, Breveglieri Michele, Furegato Martina, Folch Cinta, Ferrer Laia, Montoliu Alexandra, Nöstlinger Christiana, Vanden Berghe Wim, Kühlmann-Berenzon Sharon, Velicko Inga, Dias Sónia, Suligoi Barbara, Regine Vincenza, Stanekova Danica, Rosińska Magdalena, Caplinskas Saulius, Klavs Irena, Alexiev Ivailo, Rafila Alexandru
Veneto Region - Department of Health, CReMPE - Regional Coordination Centre for European Project Management, the Verona University Hospital, Verona, Italy.
Department of Pathology, Infectious Diseases Section, the Verona University Hospital - Veneto Region, Verona, Italy.
BMC Public Health. 2016 Mar 2;16:212. doi: 10.1186/s12889-016-2783-9.
Globally, the HIV epidemic continues to represent a pressing public health issue in Europe and elsewhere. There is an emerging and progressively urgent need to harmonise HIV and STI behavioural surveillance among MSM across European countries through the adoption of common indicators, as well as the development of trend analysis in order to monitor the HIV-STI epidemic over time. The Sialon II project protocols have been elaborated for the purpose of implementing a large-scale bio-behavioural survey among MSM in Europe in line with a Second Generation Surveillance System (SGSS) approach.
METHODS/DESIGN: Sialon II is a multi-centre biological and behavioural cross-sectional survey carried out across 13 European countries (Belgium, Bulgaria, Germany, Italy, Lithuania, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, and the UK) in community settings. A total of 4,966 MSM were enrolled in the study (3,661 participants in the TLS survey, 1,305 participants in the RDS survey). Three distinct components are foreseen in the study protocols: first, a preliminary formative research in each participating country. Second, collection of primary data using two sampling methods designed specifically for 'hard-to-reach' populations, namely Time Location Sampling (TLS) and Respondent Driven Sampling (RDS). Third, implementation of a targeted HIV/STI prevention campaign in the broader context of the data collection.
Through the implementation of combined and targeted prevention complemented by meaningful surveillance among MSM, Sialon II represents a unique opportunity to pilot a bio-behavioural survey in community settings in line with the SGSS approach in a large number of EU countries. Data generated through this survey will not only provide a valuable snapshot of the HIV epidemic in MSM but will also offer an important trend analysis of the epidemiology of HIV and other STIs over time across Europe. Therefore, the Sialon II protocol and findings are likely to contribute significantly to increasing the comparability of data in EU countries through the use of common indicators and in contributing to the development of effective public health strategies and policies in areas of high need.
在全球范围内，艾滋病毒流行在欧洲及其他地区仍然是一个紧迫的公共卫生问题。通过采用共同指标以及开展趋势分析以长期监测艾滋病毒-性传播感染疫情，在欧洲各国男男性行为者中统一艾滋病毒和性传播感染行为监测的需求日益凸显且愈发迫切。为了按照第二代监测系统（SGSS）方法在欧洲男男性行为者中开展大规模生物行为调查，已制定了Sialon II项目方案。
方法/设计：Sialon II是一项在13个欧洲国家（比利时、保加利亚、德国、意大利、立陶宛、波兰、葡萄牙、罗马尼亚、斯洛伐克、斯洛文尼亚、西班牙、瑞典和英国）的社区环境中开展的多中心生物和行为横断面调查。共有4966名男男性行为者参与了该研究（TLS调查中有3661名参与者，RDS调查中有1305名参与者）。研究方案中预计有三个不同的部分：第一，在每个参与国进行初步的形成性研究。第二，使用专门为“难以接触到的”人群设计的两种抽样方法收集原始数据，即时间地点抽样（TLS）和应答驱动抽样（RDS）。第三，在更广泛的数据收集背景下实施有针对性的艾滋病毒/性传播感染预防运动。
通过实施针对男男性行为者的联合和有针对性的预防措施，并辅以有意义的监测，Sialon II代表了一个独特的机会，可按照SGSS方法在众多欧盟国家的社区环境中试点开展生物行为调查。通过该调查产生的数据不仅将提供男男性行为者中艾滋病毒流行情况的宝贵快照，还将对欧洲各地艾滋病毒和其他性传播感染的流行病学随时间的变化提供重要的趋势分析。因此，Sialon II方案和研究结果可能会通过使用共同指标显著提高欧盟国家数据的可比性，并有助于在高需求领域制定有效的公共卫生战略和政策。
