Van Wagoner Nicholas, Elopre Latesha, Westfall Andrew O, Mugavero Michael J, Turan Janet, Hook Edward W
Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, ZRB 206, 1720 2nd Ave South, Birmingham, AL, 35294, USA.
Department of Health Care Organization and Policy, University of Alabama at Birmingham, Birmingham, AL, USA.
AIDS Behav. 2016 Aug;20(8):1706-12. doi: 10.1007/s10461-016-1347-4.
The Southeast has high rates of church attendance and HIV infection rates. We evaluated the relationship between church attendance and HIV viremia in a Southeastern US, HIV-infected cohort. Viremia (viral load ≥200 copies/ml) was analyzed 12 months after initiation of care. Univariate and multivariable logistic regression models were fit for variables potentially related to viremia. Of 382 patients, 74 % were virally suppressed at 12 months. Protective variables included church attendance (AOR 0.5; 95 % CI 0.2, 0.9), being on antiretroviral therapy (AOR 0.01; 95 % CI 0.004, 0.04), CD4(+) T lymphocyte count 200-350 cells/mm(3) at care entry (AOR 0.3; 95 % 0.1, 0.9), and education (AOR 0.5; 95 % CI 0.2, 0.9). Variables predicting viremia included black race (AOR 3.2; 95 % CI 1.4, 7.4) and selective disclosure of HIV status (AOR 2.7; 95 % CI 1.2, 5.6). Church attendance may provide needed support for patients entering HIV care for the first time.
美国东南部地区的教堂礼拜出席率和艾滋病毒感染率都很高。我们在美国东南部一个感染艾滋病毒的队列中评估了教堂礼拜出席率与艾滋病毒病毒血症之间的关系。在开始治疗12个月后分析病毒血症（病毒载量≥200拷贝/毫升）情况。对可能与病毒血症相关的变量进行单变量和多变量逻辑回归模型分析。在382名患者中，74%在12个月时病毒得到抑制。具有保护作用的变量包括教堂礼拜出席率（调整后比值比[AOR]为0.5；95%置信区间[CI]为0.2至0.9）、接受抗逆转录病毒治疗（AOR为0.01；95%CI为0.004至0.04）、开始治疗时CD4(+)T淋巴细胞计数为200 - 350个细胞/立方毫米（AOR为0.3；95%CI为0.1至0.9）以及受教育程度（AOR为0.5；95%CI为0.2至0.9）。预测病毒血症的变量包括黑人种族（AOR为3.2；95%CI为1.4至7.4）和选择性披露艾滋病毒感染状况（AOR为2.7；95%CI为1.2至5.6）。教堂礼拜出席率可能为首次接受艾滋病毒治疗的患者提供所需的支持。
