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猫髋关节发育不良:识别与治疗的挑战。

Feline hip dysplasia: A challenge to recognise and treat.

作者信息

Perry Karen

机构信息

Veterinary Medical Center, Michigan State University, 736 Wilson Road, East Lansing, MI 48824-1314, USA

出版信息

J Feline Med Surg. 2016 Mar;18(3):203-18. doi: 10.1177/1098612X16631227.

Abstract

PRACTICAL RELEVANCE

The reported incidence of hip dysplasia (HD) in cats varies dramatically between studies, but the condition is likely more common than we realise. There is little doubt that cats with HD and associated osteoarthritis (OA) suffer pain, and this warrants appropriate therapy.

DIAGNOSTIC CHALLENGES

Clinical signs of HD in cats are often gradual in onset, making them difficult to appreciate, but may include inactivity, pelvic limb lameness, difficulty jumping and climbing stairs, and reluctance to squat to defecate. Often lameness is bilateral, and can be particularly difficult to recognise. The most common radiographic finding is an abnormally shallow acetabulum. Subluxation, however, is not consistently associated with OA in cats and therefore the role that joint laxity plays in disease progression remains uncertain. Degenerative changes of the femoral head and neck seem to develop later than in the dog, and are less marked.

THERAPEUTIC CHALLENGES

The majority of cats respond to non-surgical management with environmental modulation, physical therapy, dietary modulation, weight loss, nutraceuticals and drug therapy. Should non-surgical management not provide sufficient relief, two salvage surgical options are available: femoral head and neck excision (FHNE) and total hip replacement (THR). While there is a risk of complications with micro-THR, the positive outcomes that have been reported indicate that it should be considered in the treatment of coxofemoral pathology in cats in the same way that THR is considered for larger dogs, especially given the inconsistent results associated with FHNE. Monitoring the effect of treatment is challenging as the assessment of pain in cats is complex and there is no validated scoring system or owner-completed questionnaire yet available for cats.

EVIDENCE BASE

There is a paucity of clinical reports focusing solely on HD in cats. The author draws on a combination of published studies, in cats, dogs and humans, as well as personal clinical experience.

摘要

实际相关性

猫髋关节发育不良(HD)的报告发病率在不同研究之间差异很大,但这种情况可能比我们意识到的更为常见。毫无疑问,患有HD及相关骨关节炎(OA)的猫会遭受疼痛,这需要适当的治疗。

诊断挑战

猫HD的临床症状通常起病缓慢,难以察觉,但可能包括活动减少、后肢跛行、跳跃和爬楼梯困难以及不愿蹲下排便。跛行通常是双侧的,尤其难以识别。最常见的放射学表现是髋臼异常浅。然而,半脱位在猫中与OA并不总是相关,因此关节松弛在疾病进展中所起的作用仍不确定。股骨头和颈部的退行性变化似乎比狗出现得晚,且程度较轻。

治疗挑战

大多数猫对通过环境调节、物理治疗、饮食调节、体重减轻、营养保健品和药物治疗等非手术管理有反应。如果非手术管理不能提供足够的缓解,有两种挽救性手术选择:股骨头和颈部切除术(FHNE)和全髋关节置换术(THR)。虽然微型THR有并发症风险,但已报道的积极结果表明,在治疗猫的髋股关节病变时应像考虑对大型犬进行THR一样考虑它,特别是鉴于FHNE的结果不一致。由于评估猫的疼痛很复杂,且目前尚无经过验证的评分系统或主人填写的问卷,因此监测治疗效果具有挑战性。

证据基础

专门针对猫HD的临床报告很少。作者借鉴了在猫、狗和人类中发表的研究以及个人临床经验。

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