Stankovic Uros, Ploeger Lennert S, Sonke Jan-Jakob, van Herk Marcel
Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
Med Phys. 2016 Mar;43(3):1057-64. doi: 10.1118/1.4941015.
Image lag in the flat-panel detector used for Linac integrated cone beam computed tomography (CBCT) has a degrading effect on CBCT image quality. The most prominent visible artifact is the presence of bright semicircular structure in the transverse view of the scans, known also as radar artifact. Several correction strategies have been proposed, but until now the clinical introduction of such corrections remains unreported. In November 2013, the authors have clinically implemented a previously proposed image lag correction on all of their machines at their main site in Amsterdam. The purpose of this study was to retrospectively evaluate the effect of the correction on the quality of CBCT images and evaluate the required calibration frequency.
Image lag was measured in five clinical CBCT systems (Elekta Synergy 4.6) using an in-house developed beam interrupting device that stops the x-ray beam midway through the data acquisition of an unattenuated beam for calibration. A triple exponential falling edge response was fitted to the measured data and used to correct image lag from projection images with an infinite response. This filter, including an extrapolation for saturated pixels, was incorporated in the authors' in-house developed clinical cbct reconstruction software. To investigate the short-term stability of the lag and associated parameters, a series of five image lag measurement over a period of three months was performed. For quantitative analysis, the authors have retrospectively selected ten patients treated in the pelvic region. The apparent contrast was quantified in polar coordinates for scans reconstructed using the parameters obtained from different dates with and without saturation handling.
Visually, the radar artifact was minimal in scans reconstructed using image lag correction especially when saturation handling was used. In patient imaging, there was a significant reduction of the apparent contrast from 43 ± 16.7 to 15.5 ± 11.9 HU without the saturation handling and to 9.6 ± 12.1 HU with the saturation handling, depending on the date of the calibration. The image lag correction parameters were stable over a period of 3 months. The computational load was increased by approximately 10%, not endangering the fast in-line reconstruction.
The lag correction was successfully implemented clinically and removed most image lag artifacts thus improving the image quality. Image lag correction parameters were stable for 3 months indicating low frequency of calibration requirements.
用于直线加速器集成锥形束计算机断层扫描(CBCT)的平板探测器中的图像滞后会对CBCT图像质量产生降级影响。最明显的可见伪影是扫描横向视图中存在明亮的半圆形结构,也称为雷达伪影。已经提出了几种校正策略,但到目前为止,此类校正的临床应用尚未见报道。2013年11月,作者在阿姆斯特丹主要站点的所有机器上临床实施了先前提出的图像滞后校正。本研究的目的是回顾性评估该校正对CBCT图像质量的影响,并评估所需的校准频率。
使用内部开发的束中断装置在五个临床CBCT系统(Elekta Synergy 4.6)中测量图像滞后,该装置在未衰减束的数据采集中途停止x射线束以进行校准。将三重指数下降沿响应拟合到测量数据,并用于校正具有无限响应的投影图像中的图像滞后。该滤波器,包括对饱和像素的外推,被纳入作者内部开发的临床CBCT重建软件中。为了研究滞后及相关参数的短期稳定性,在三个月的时间内进行了一系列五次图像滞后测量。为了进行定量分析,作者回顾性选择了十名在盆腔区域接受治疗的患者。对于使用从不同日期获得的参数重建的扫描,在有无饱和处理的情况下,在极坐标中对表观对比度进行了量化。
在视觉上,使用图像滞后校正重建的扫描中雷达伪影最小,特别是在使用饱和处理时。在患者成像中,根据校准日期,表观对比度从43±16.7显著降低到15.5±11.9 HU(无饱和处理)和9.6±12.1 HU(有饱和处理)。图像滞后校正参数在3个月内保持稳定。计算负荷增加了约10%,但不危及快速在线重建。
滞后校正已在临床上成功实施,并消除了大多数图像滞后伪影,从而提高了图像质量。图像滞后校正参数在3个月内保持稳定,表明校准要求的频率较低。