Zhao Yanglu, Wong Nathan
Heart Disease Prevention Program, Division of Cardiology, C240, Medical Sciences, University of California, Irvine, CA, 92697, USA.
F1000Res. 2015 Oct 28;4. doi: 10.12688/f1000research.6625.1. eCollection 2015.
Diabetes mellitus is associated with greater risks for cardiovascular diseases (CVD). Multiple noninvasive screening tools for CVD including cardiac CT, carotid intima-media thickness test, myocardial perfusion imaging have been examined in those with diabetes, but the prognostic value of these tests vary and issues remain regarding their cost-benefit ratios, potential harms of radiation, and how they fit into screening algorithms for CVD. We discuss in this report the needs and criteria for screening tests and summarize the evidence from observational studies and clinical trials. We also explore whether there should be more sensitive screening modalities to better detect both short and long-term cardiovascular risk among asymptomatic patients with diabetes.
糖尿病与心血管疾病（CVD）的更高风险相关。已经在糖尿病患者中对多种用于CVD的非侵入性筛查工具进行了检查，包括心脏CT、颈动脉内膜中层厚度测试、心肌灌注成像，但这些测试的预后价值各不相同，并且在其成本效益比、辐射潜在危害以及它们如何纳入CVD筛查算法方面仍存在问题。我们在本报告中讨论了筛查测试的需求和标准，并总结了观察性研究和临床试验的证据。我们还探讨了是否应该有更敏感的筛查方式，以更好地检测无症状糖尿病患者的短期和长期心血管风险。
