Arrhythmia as a cardiac manifestation in MELAS syndrome.
作者信息
Thomas Tamara, Craigen William J, Moore Ryan, Czosek Richard, Jefferies John L
机构信息
Arkansas Children's Hospital, Little Rock, AR, United States.
Texas Children's Genetics Clinic, Texas Children's Hospital, Houston, TX, United States.
出版信息
Mol Genet Metab Rep. 2015 Jun 3;4:9-10. doi: 10.1016/j.ymgmr.2015.05.002. eCollection 2015 Sep.
Abstract
A 44-year-old female with a diagnosis of mitochondrial myopathy, encephalopathy and stroke-like episodes (MELAS) syndrome had progressive left ventricular hypertrophy (LVH) on echocardiogram. A Holter monitor demonstrated episodes of non-sustained atrial tachycardia, a finding not been previously described in this population. This unique case of MELAS syndrome demonstrates the known associated cardiac manifestation of LVH and the new finding of atrial tachycardia which may represent the potential for subclinical arrhythmia in this population.
摘要
相似文献
1
Arrhythmia as a cardiac manifestation in MELAS syndrome.
Mol Genet Metab Rep. 2015 Jun 3;4:9-10. doi: 10.1016/j.ymgmr.2015.05.002. eCollection 2015 Sep.
2
Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome.
Diagnostics (Basel). 2021 Feb 12;11(2):295. doi: 10.3390/diagnostics11020295.
3
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) decrease in diastolic left ventricular function assessed by echocardiography.
Pediatr Cardiol. 1993 Jul;14(3):162-6. doi: 10.1007/BF00795646.
4
MELAS syndrome and cardiomyopathy: linking mitochondrial function to heart failure pathogenesis.
Heart Fail Rev. 2016 Jan;21(1):103-116. doi: 10.1007/s10741-015-9524-5.
5
[Mitochondrial myopathy, encephalopathy, lactate acidosis with stroke-like episodes syndrome (MELAS): a case report].
Srp Arh Celok Lek. 2012 May-Jun;140(5-6):355-8. doi: 10.2298/sarh1206355p.
6
Treatment options for mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome.
Pharmacotherapy. 2010 Nov;30(11):1179-96. doi: 10.1592/phco.30.11.1179.
7
The mitochondrial myopathy encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options.
CNS Drugs. 2006;20(6):443-64. doi: 10.2165/00023210-200620060-00002.
8
[Cardiac involvement in mitochondrial disease: a clinical study of 38 patients].
Igaku Kenkyu. 1991 Sep;61(2):49-61.
9
A follow-up study in a Taiwanese family with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes syndrome.
J Formos Med Assoc. 2007 Jul;106(7):528-36. doi: 10.1016/S0929-6646(07)60003-5.
10
Stroke and Stroke-like Episodes in Muscle Disease.
Open Neurol J. 2012;6:26-36. doi: 10.2174/1874205X01206010026. Epub 2012 May 18.
引用本文的文献
1
A Review over Mitochondrial Diseases Due to mtDNA Mutations: Recent Advances and Remedial Aspects.
Infect Disord Drug Targets. 2025;25(3):e18715265304029. doi: 10.2174/0118715265304029240801092834.
2
Rare Phenotypic Manifestations of MELAS.
Yonsei Med J. 2020 Oct;61(10):904-906. doi: 10.3349/ymj.2020.61.10.904.
3
Mitochondrial diseases caused by mtDNA mutations: a mini-review.
Ther Clin Risk Manag. 2018 Oct 9;14:1933-1942. doi: 10.2147/TCRM.S154863. eCollection 2018.
4
Sea food consumption for improving cardiac and cerebral manifestations of mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes.
Ann Transl Med. 2017 Sep;5(17):369. doi: 10.21037/atm.2017.07.02.
5
Arrhythmias in MELAS syndrome.
Mol Genet Metab Rep. 2016 Apr 14;7:54. doi: 10.1016/j.ymgmr.2016.03.008. eCollection 2016 Jun.
本文引用的文献
1
Treatment of central nervous system manifestations in mitochondrial disorders.
Eur J Neurol. 2011 Jan;18(1):28-38. doi: 10.1111/j.1468-1331.2010.03086.x.
2
Prevalence and natural history of heart disease in adults with primary mitochondrial respiratory chain disease.
Eur J Heart Fail. 2010 Feb;12(2):114-21. doi: 10.1093/eurjhf/hfp186.
3
Clinical presentations of mitochondrial cardiomyopathies.
Pediatr Cardiol. 2004 Sep-Oct;25(5):443-50. doi: 10.1007/s00246-003-0490-7. Epub 2004 Jun 8.
4
Impact of atrial fibrillation on the clinical course of hypertrophic cardiomyopathy.
Circulation. 2001 Nov 20;104(21):2517-24. doi: 10.1161/hc4601.097997.
5
Mitochondrial defects in neurodegenerative disease.
Ment Retard Dev Disabil Res Rev. 2001;7(3):158-66. doi: 10.1002/mrdd.1023.
6
Atrial fibrillation in hypertrophic cardiomyopathy: a longitudinal study.
J Am Coll Cardiol. 1990 May;15(6):1279-85. doi: 10.1016/s0735-1097(10)80014-2.
Zotero 插件