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关于CYB5D2对HeLa宫颈癌细胞周期分布影响的数据集。

Dataset on the effects of CYB5D2 on the distribution of HeLa cervical cancer cell cycle.

作者信息

Xie Yanyun, Shen Yen Ting, Kapoor Anil, Ojo Diane, Wei Fengxiang, De Melo Jason, Lin Xiaozeng, Wong Nicholas, Yan Judy, Tao Lijian, Major Pierre, Tang Damu

机构信息

Division of Nephrology, Department of Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, PR China; Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O'Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph's Hospital, Canada.

Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O'Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph's Hospital, Canada.

出版信息

Data Brief. 2016 Jan 28;6:811-6. doi: 10.1016/j.dib.2016.01.036. eCollection 2016 Mar.

Abstract

We have recently reported that CYB5D2 plays a role in suppression of cervical cancer tumorigenesis, "CYB5D2 displays tumor suppression activities towards cervical cancer" [1]. We provide the accompany data here describing the effects of CYB5D2 overexpression and addition of recombinant CYB5D2 on HeLa cell cycle distribution. Furthermore, we will present the conditions used to specifically determine CYB5D2 expression in primary cervical and cervical cancer tissues using immunohistochemistry (IHC) and the patient cohort involved in assessing the CYB5D2 protein levels in primary cervical and cervical cancer tissues.

摘要

我们最近报道CYB5D2在抑制宫颈癌肿瘤发生中发挥作用,“CYB5D2对宫颈癌具有肿瘤抑制活性”[1]。我们在此提供伴随数据,描述CYB5D2过表达以及添加重组CYB5D2对HeLa细胞周期分布的影响。此外,我们将介绍使用免疫组织化学(IHC)特异性测定原发性宫颈组织和宫颈癌组织中CYB5D2表达的条件,以及参与评估原发性宫颈组织和宫颈癌组织中CYB5D2蛋白水平的患者队列。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88dc/4749936/1ac38f954c47/gr1.jpg

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