Liggins Casandra A, Ma Ly T, Schlumbrecht Matthew P
Department of Obstetrics and Gynecology at Banner University Medical Center, Phoenix, AZ, USA.
Department of Pathology, Banner MD Anderson Cancer Center, Gilbert, AZ, USA.
Gynecol Oncol Rep. 2015 Dec 24;15:16-9. doi: 10.1016/j.gore.2015.12.003. eCollection 2016 Jan.
Sertoli-Leydig cell tumors are rare sex-cord stromal tumors of the ovary that can present with a variety of histological elements, which may complicate diagnosis and treatment.
A 40-year-old female presenting with pelvic pain is found to have a large complex right adnexal mass and elevated alpha-fetoprotein. The mass was diagnosed as a Sertoli-Leydig cell tumor with heterologous elements including carcinoid and hepatoid components. She was treated with surgical resection followed by adjuvant chemotherapy and remains clear of disease.
Prognostic indicators for Sertoli-Leydig cell tumors include degree and type of heterologous element differentiation. Thorough characterization of such elements is crucial for adequate diagnosis and treatment.
支持-间质细胞瘤是卵巢罕见的性索间质肿瘤，可呈现多种组织学成分，这可能使诊断和治疗复杂化。
一名40岁女性因盆腔疼痛就诊，发现右侧附件有一个大的复杂肿块，甲胎蛋白升高。该肿块被诊断为具有异源性成分（包括类癌和肝样成分）的支持-间质细胞瘤。她接受了手术切除，随后进行辅助化疗，目前疾病无复发。
支持-间质细胞瘤的预后指标包括异源性成分分化的程度和类型。对此类成分进行全面表征对于充分的诊断和治疗至关重要。
