卵巢支持-间质细胞瘤：诊断难题。
Sertoli-Leydig cell tumor of the ovary: A diagnostic dilemma.
作者信息
Liggins Casandra A, Ma Ly T, Schlumbrecht Matthew P
机构信息
Department of Obstetrics and Gynecology at Banner University Medical Center, Phoenix, AZ, USA.
Department of Pathology, Banner MD Anderson Cancer Center, Gilbert, AZ, USA.
出版信息
Gynecol Oncol Rep. 2015 Dec 24;15:16-9. doi: 10.1016/j.gore.2015.12.003. eCollection 2016 Jan.
BACKGROUND
Sertoli-Leydig cell tumors are rare sex-cord stromal tumors of the ovary that can present with a variety of histological elements, which may complicate diagnosis and treatment.
CASE
A 40-year-old female presenting with pelvic pain is found to have a large complex right adnexal mass and elevated alpha-fetoprotein. The mass was diagnosed as a Sertoli-Leydig cell tumor with heterologous elements including carcinoid and hepatoid components. She was treated with surgical resection followed by adjuvant chemotherapy and remains clear of disease.
CONCLUSION
Prognostic indicators for Sertoli-Leydig cell tumors include degree and type of heterologous element differentiation. Thorough characterization of such elements is crucial for adequate diagnosis and treatment.
背景
支持-间质细胞瘤是卵巢罕见的性索间质肿瘤，可呈现多种组织学成分，这可能使诊断和治疗复杂化。
病例
一名40岁女性因盆腔疼痛就诊，发现右侧附件有一个大的复杂肿块，甲胎蛋白升高。该肿块被诊断为具有异源性成分（包括类癌和肝样成分）的支持-间质细胞瘤。她接受了手术切除，随后进行辅助化疗，目前疾病无复发。
结论
支持-间质细胞瘤的预后指标包括异源性成分分化的程度和类型。对此类成分进行全面表征对于充分的诊断和治疗至关重要。
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