Department of Respiratory Medicine, Homerton University Hospital NHS Foundation Trust, London, UK.
Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
NPJ Prim Care Respir Med. 2016 Mar 3;26:15081. doi: 10.1038/npjpcrm.2015.81.
Chronic cough is common in the community and can cause significant morbidity. It is not clear how closely treatment guidelines are used in general practice, or how often specialist referral is indicated. We aimed to assess the management of chronic cough in primary care before referral to a cough clinic, and to assess the outcome of managing chronic cough with an approach of simple investigation and empirical treatment trials. Data were extracted from the records of all patients attending a district general hospital respiratory clinic over a two-year period with isolated chronic cough lasting ⩾8 weeks. The clinic assessed symptoms with a cough-severity visual analogue scale and the Leicester Cough Questionnaire. Among 266 patients, the most frequent diagnoses were asthma (29%), gastro-oesophageal reflux (22%) and angiotensin-converting enzyme inhibitor use (14%). In all, 12% had unexplained chronic cough. Common diagnoses had often not been excluded in primary care: only 21% had undergone spirometry, 86% had undergone chest radiography and attempts to exclude asthma with corticosteroids had been made only in 39%. In the clinic few investigations were conducted that were not available in primary care. Substantial improvements in symptoms occurred with a median (interquartile range) total of 2 (2-3) clinic visits. We estimated that 87% of patients could have been managed solely in primary care; we did not identify distinguishing characteristics among this group. Most cases of chronic cough referred to secondary care could be managed with a simple and systematic approach, which is potentially transferrable to a community setting.
慢性咳嗽在社区中很常见,会导致很大的发病率。目前尚不清楚一般实践中治疗指南的使用情况有多密切,也不清楚专家转诊的频率如何。我们旨在评估在转诊至咳嗽诊所之前,初级保健中慢性咳嗽的管理情况,并评估通过简单调查和经验性治疗试验来管理慢性咳嗽的效果。从在两年内因孤立性慢性咳嗽持续 ⩾8 周而就诊于地区综合医院呼吸诊所的所有患者的记录中提取数据。该诊所使用咳嗽严重程度视觉模拟量表和莱斯特咳嗽问卷评估症状。在 266 名患者中,最常见的诊断是哮喘(29%)、胃食管反流(22%)和血管紧张素转换酶抑制剂使用(14%)。在所有患者中,有 12%的患者患有不明原因的慢性咳嗽。在初级保健中,常见的诊断通常尚未排除:仅 21%的患者进行了肺功能检查,86%的患者进行了胸部 X 光检查,仅 39%的患者尝试用皮质类固醇排除哮喘。在诊所中进行的许多检查在初级保健中都可以进行。通过中位数(四分位距)2(2-3)次就诊,症状得到了显著改善。我们估计 87%的患者可以仅在初级保健中进行管理;我们没有在该组中发现可区分的特征。大多数转诊至二级保健的慢性咳嗽病例都可以通过简单而系统的方法进行管理,这种方法可能适用于社区环境。