Qi Fenglian, Xu Yudong, Meng Zihui, Xue Min, Xu Zhibin, Qiu Lili, Cui Kejian
Se Pu. 2015 Nov;33(11):1134-9. doi: 10.3724/sp.j.1123.2015.09005.
Cucurbit [n] urils (CB [n]), a kind of host molecules of the fourth generation supramolecule followed crown ethers, cyclodextrins and calixarenes in supramolecular chemistry, are macrocyclic ligands and consist of several glycoluril units. Their special molecular recognition based on unique separation selectivity and stability have gained great interest in supramolecular chemistry and chromatography. Hereby, we give a review of research progresses of cucurbit [n] urils structural features, its homologues and derivatives and their applications in chromatographic stationary phase.
葫芦[n]脲（CB[n]）是继冠醚、环糊精和杯芳烃之后超分子化学领域的第四代主体分子，属于大环配体，由多个甘脲单元组成。它们基于独特的分离选择性和稳定性所具有的特殊分子识别能力，在超分子化学和色谱领域引起了极大的关注。在此，我们综述了葫芦[n]脲的结构特征、同系物和衍生物及其在色谱固定相中的应用研究进展。
