Bajaj Navkaranbir S, Singh Siddharth, Farag Ayman, El-Hajj Stephanie, Heo Jack, Iskandrian Ami E, Hage Fadi G
Division of Cardiovascular Disease, University of Alabama at Birmingham, Lyons Harrison Research Building 306, 701 19th Street South, Birmingham, AL, 35294-0007, USA.
Division of Cardiovascular Disease, Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA.
J Nucl Cardiol. 2016 Jun;23(3):390-413. doi: 10.1007/s12350-016-0441-3. Epub 2016 Mar 3.
Myocardial perfusion imaging (MPI) is an established diagnostic test that provides useful prognostic data in patients with known or suspected coronary artery disease. In more than half of the patients referred for stress testing, vasodilator stress is used in lieu of exercise. Unlike exercise, vasodilator stress does not provide information on exercise and functional capacity, heart rate recovery, and chronotropy, and ECG changes are less frequent. These non-perfusion data provide important prognostic and patient management information. Further, event rates in patients undergoing vasodilator MPI are higher than in those undergoing exercise MPI and even in those with normal images probably due to higher pretest risk. However, there are a number of non-perfusion variables that are obtained during vasodilator stress testing, which have prognostic relevance but their use has not been well emphasized. The purpose of this review is to summarize the prognostic values of these non-perfusion data obtained during vasodilator MPI.
心肌灌注成像（MPI）是一项已确立的诊断测试，可为已知或疑似冠状动脉疾病的患者提供有用的预后数据。在超过一半接受负荷试验的患者中，使用血管扩张剂负荷代替运动负荷。与运动不同，血管扩张剂负荷不能提供有关运动和功能能力、心率恢复以及变时性的信息，而且心电图变化较少见。这些非灌注数据提供了重要的预后和患者管理信息。此外，接受血管扩张剂MPI检查的患者的事件发生率高于接受运动MPI检查的患者，甚至高于图像正常的患者，这可能是由于检查前风险较高。然而，在血管扩张剂负荷试验期间可获得一些非灌注变量，它们具有预后相关性，但尚未得到充分重视。本综述的目的是总结在血管扩张剂MPI期间获得的这些非灌注数据的预后价值。
