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经皮高能微波消融治疗肺部肿瘤:一项单中心回顾性研究

Percutaneous High-Energy Microwave Ablation for the Treatment of Pulmonary Tumors: A Retrospective Single-Center Experience.

作者信息

Egashira Yoshiaki, Singh Saurabh, Bandula Steve, Illing Rowland

机构信息

Interventional Oncology Service, University College London Hospital, London, United Kingdom; Department of Radiology, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan.

Centre for Medical Imaging, University College London, London, United Kingdom.

出版信息

J Vasc Interv Radiol. 2016 Apr;27(4):474-9. doi: 10.1016/j.jvir.2016.01.001. Epub 2016 Mar 2.

Abstract

PURPOSE

To evaluate the safety and efficacy of percutaneous high-energy microwave ablation (MWA) for the treatment for pulmonary tumors.

MATERIALS AND METHODS

A retrospective review was undertaken of 44 patients (21 men, 23 women; median age, 66 y; range, 17-89 y) who underwent 62 sessions of high-energy MWA for 87 pulmonary tumors at a single tertiary referral center between June 2012 and June 2014. Primary tumor origin was sarcoma (n = 23), colorectal (n = 16), lung (n = 2), esophageal (n = 1), breast (n = 1), and bladder (n = 1). Median tumor size was 12 mm (range, 6-45 mm). Technical success was recorded contemporaneously, complication rate at 30 days was recorded prospectively, and technique effectiveness was assessed by longitudinal follow-up CT scan.

RESULTS

Primary technical success was achieved in 94% of ablation sessions. The median follow-up interval was 15 months (range, 6.2-29.5 mo) during which time local tumor progression was observed in two of 87 tumors (technique effectiveness 98%). Pneumothorax requiring chest tube insertion occurred in 19%; delayed pneumothorax occurred in four patients. No hemoptysis, infection, or other complications were recorded.

CONCLUSIONS

High-energy MWA is safe and effective for the destruction of lung tumors.

摘要

目的

评估经皮高能微波消融(MWA)治疗肺部肿瘤的安全性和有效性。

材料与方法

回顾性分析了2012年6月至2014年6月期间在一家三级转诊中心接受62次高能MWA治疗87个肺部肿瘤的44例患者(男性21例,女性23例;年龄中位数66岁;范围17 - 89岁)。原发肿瘤起源为肉瘤(n = 23)、结直肠癌(n = 16)、肺癌(n = 2)、食管癌(n = 1)、乳腺癌(n = 1)和膀胱癌(n = 1)。肿瘤大小中位数为12 mm(范围6 - 45 mm)。同步记录技术成功率,前瞻性记录30天并发症发生率,并通过纵向随访CT扫描评估技术有效性。

结果

94%的消融疗程取得了初步技术成功。中位随访间隔为15个月(范围6.2 - 29.5个月),在此期间87个肿瘤中有2个出现局部肿瘤进展(技术有效性98%)。需要插入胸管的气胸发生率为19%;4例患者出现延迟性气胸。未记录到咯血、感染或其他并发症。

结论

高能MWA对肺部肿瘤的破坏是安全有效的。

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