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毛细管电泳-化学发光检测在临床、环境和食品分析中的应用。综述。

Applications of capillary electrophoresis with chemiluminescence detection in clinical, environmental and food analysis. A review.

作者信息

Lara Francisco J, Airado-Rodríguez Diego, Moreno-González David, Huertas-Pérez José F, García-Campaña Ana M

机构信息

Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Campus Fuentenueva s/n, 18071 Granada, Spain.

Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Campus Fuentenueva s/n, 18071 Granada, Spain.

出版信息

Anal Chim Acta. 2016 Mar 24;913:22-40. doi: 10.1016/j.aca.2016.01.046. Epub 2016 Feb 1.

DOI:10.1016/j.aca.2016.01.046
PMID:26944987
Abstract

This paper reviews the latest developments and analytical applications of chemiluminescence detection coupled to capillary electrophoresis (CE-CL). Different sections considering the most common CL systems have been included, such as the tris(2,2'-bipyridine)ruthenium(II) system, the luminol and acridinium derivative reactions, the peroxyoxalate CL or direct oxidations. Improvements in instrumental designs, new strategies for improving both resolution and sensitivity, and applications in different fields such as clinical, pharmaceutical, environmental and food analysis have been included. This review covers the literature from 2010 to 2015.

摘要

本文综述了化学发光检测与毛细管电泳联用(CE-CL)的最新进展及其分析应用。文中包含了不同部分,涉及最常见的化学发光体系,如三(2,2'-联吡啶)钌(II)体系、鲁米诺和吖啶鎓衍生物反应、过氧草酸酯化学发光或直接氧化反应。还介绍了仪器设计的改进、提高分辨率和灵敏度的新策略,以及在临床、制药、环境和食品分析等不同领域的应用。本综述涵盖了2010年至2015年的文献。

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