Liu Yuxuan, Huang Xiangyi, Ren Jicun
State Key Laboratory of Metal Matrix Composites, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, P. R. China.
Electrophoresis. 2016 Jan;37(1):2-18. doi: 10.1002/elps.201500314. Epub 2015 Oct 9.
CE is an ideal analytical method for extremely volume-limited biological microenvironments. However, the small injection volume makes it a challenge to achieve highly sensitive detection. Chemiluminescence (CL) detection is characterized by providing low background with excellent sensitivity because of requiring no light source. The coupling of CL with CE and MCE has become a powerful analytical method. So far, this method has been widely applied to chemical analysis, bioassay, drug analysis, and environment analysis. In this review, we first introduce some developments for CE-CL and MCE-CL systems, and then put the emphasis on the applications in the last 10 years. Finally, we discuss the future prospects.
毛细管电泳是用于极其微量生物微环境的理想分析方法。然而，进样体积小使得实现高灵敏度检测成为一项挑战。化学发光（CL）检测的特点是无需光源，背景低且灵敏度高。化学发光与毛细管电泳和微流控毛细管电泳的联用已成为一种强大的分析方法。到目前为止，该方法已广泛应用于化学分析、生物测定、药物分析和环境分析。在本综述中，我们首先介绍毛细管电泳 - 化学发光和微流控毛细管电泳 - 化学发光系统的一些进展，然后重点阐述过去十年中的应用。最后，我们讨论未来前景。
