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阑尾巨大黏液腺癌:一例报告

Giant mucinous adenocarcinoma of the appendix: a case report.

作者信息

Dang Sheng-Chun, Sun Ming-Ming, Liu Lu-Lu, Malik Abdul, Zhang Jian-Xin, Fan Yi-Yi, Zou Song, Cui Lei, Qu Jian-Guo, Chen Ji-Xiang

机构信息

Department of General Surgery, The Affiliated Hospital of Jiangsu University, No. 438 Jiefang Road, Zhenjiang, 212001, Jiangsu Province, China.

出版信息

J Med Case Rep. 2017 Jul 31;11(1):206. doi: 10.1186/s13256-017-1385-1.

Abstract

BACKGROUND

Appendiceal mucinous adenocarcinoma is an extremely rare disease in clinical practice. Here, we report a case of unprecedented size that occupied the entire abdomen of a man.

CASE PRESENTATION

A 49-year-old Chinese Han man presented with symptoms of abdominal distension. During a computed tomography imaging examination, a cystic-solid mass that occupied his entire abdominal cavity was detected. During exploratory laparotomy, an appendiceal tumor in his abdominal-pelvic cavity measuring 27.6 × 14.2 cm was found, and he underwent tumor resection. The pathology of the tumor identified a well-differentiated appendiceal mucinous adenocarcinoma with mucin infiltrating into the soft tissue of the lump edge and omentum tissue. After surgery, our patient accepted intraperitoneal infusion chemotherapy. At present, he has had no recurrence for 15 months.

CONCLUSIONS

To the best of our knowledge, the present case is the largest appendiceal mucinous adenocarcinoma reported. Surgical tumor resection is the preferred treatment for appendiceal mucinous adenocarcinoma. This is supplemented by chemotherapy which can further prolong survival.

摘要

背景

阑尾黏液腺癌在临床实践中是一种极其罕见的疾病。在此,我们报告一例前所未有的巨大阑尾黏液腺癌病例,该肿瘤占据了一名男性患者的整个腹腔。

病例介绍

一名49岁的中国汉族男性患者出现腹胀症状。在计算机断层扫描成像检查中,发现一个占据其整个腹腔的囊实性肿块。在剖腹探查术中,发现其腹盆腔有一个大小为27.6×14.2 cm的阑尾肿瘤,随后患者接受了肿瘤切除术。肿瘤病理检查确定为高分化阑尾黏液腺癌,黏液浸润至肿块边缘的软组织和大网膜组织。术后,该患者接受了腹腔灌注化疗。目前,患者已无复发存活15个月。

结论

据我们所知,本病例是已报道的最大的阑尾黏液腺癌病例。手术切除肿瘤是阑尾黏液腺癌的首选治疗方法。化疗作为补充治疗可进一步延长患者生存期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a630/5535295/c649c7a1b769/13256_2017_1385_Fig1_HTML.jpg

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