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情绪应激作为应激性心肌病的触发因素:一例报告及文献综述

An Emotional Stress as a Trigger for Reverse Takotsubo Cardiomyopathy: A Case Report and Literature Review.

作者信息

Barbaryan Aram, Bailuc Stefania L, Patel Krishan, Raqeem Muhammad Wajih, Thakur Atul, Mirrakhimov Aibek E

机构信息

Department of Internal Medicine, Hospital Sisters Health System - St. Mary's Hospital, Decatur, IL, USA.

Hospital Medicine, Cleveland Clinic, Cleveland, OH, USA.

出版信息

Am J Case Rep. 2016 Mar 6;17:137-42. doi: 10.12659/ajcr.896549.

Abstract

BACKGROUND

Reverse Takotsubo cardiomyopathy is one of the rarest types of stress-induced cardiomyopathy, which despite sharing similar pathogenic mechanisms with its more common counterpart, has different clinical manifestations, demographics, and laboratory values.

CASE REPORT

We present the case of a 61-year-old woman who came to the hospital with a chief complaint of chest pain and dyspnea. She was found to have elevated troponin and severely depressed left ventricular function. Echocardiography showed normal contracting apex, with the rest of the left ventricle being hypokinetic. Cardiac catheterization revealed mild coronary artery disease and confirmed echocardiographic findings showing hyperkinetic apex and dilated base. She was discharged home on ACE inhibitor and B-blocker. A repeat echocardiogram 2 weeks after the initial presentation showed complete resolution of cardiac dysfunction.

CONCLUSIONS

Reverse Takotsubo cardiomyopathy is a rare disease mimicking acute coronary syndrome. It is essential to rule out organic coronary disease prior to attributing the presentation to Takotsubo cardiomyopathy. With supportive care, the long-term prognosis is good in the vast majority of patients.

摘要

背景

反向性应激性心肌病是应激性心肌病中最罕见的类型之一,尽管其与更常见的应激性心肌病具有相似的致病机制,但临床表现、人口统计学特征及实验室检查值有所不同。

病例报告

我们报告一例61岁女性患者,因胸痛和呼吸困难为主诉前来就诊。发现其肌钙蛋白升高,左心室功能严重受损。超声心动图显示心尖部收缩正常,左心室其余部分运动减弱。心脏导管检查显示轻度冠状动脉疾病,并证实了超声心动图结果,即心尖部运动亢进和心底扩大。她出院时服用血管紧张素转换酶抑制剂和β受体阻滞剂。首次就诊2周后复查超声心动图显示心脏功能障碍完全缓解。

结论

反向性应激性心肌病是一种罕见的模仿急性冠状动脉综合征的疾病。在将临床表现归因于应激性心肌病之前,排除器质性冠状动脉疾病至关重要。通过支持性治疗,绝大多数患者的长期预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a34b/4784546/548198a931f4/amjcaserep-17-137-g001.jpg

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