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三伏贴治疗变应性鼻炎的近期疗效及不良反应

[Short effect and adverse reaction of dog days plaster for allergic rhinitis].

作者信息

Zhang Hongli, Zhao Minghui, Fu Lixin

出版信息

Zhongguo Zhen Jiu. 2016 Jan;36(1):33-6.

Abstract

OBJECTIVE

To evaluate the short effect and safety of the acupoint application of dog days for allergic rhinitis.

METHODS

Two hundred and forty-nine patients were randomly divided into an application group (166 cases) and a placebo group (83 cases). On the first day of the first dog days, the first day of the second of the three ten-day periods of the hot season and the first day of the last of the three ten-day periods of the hot season, acupoint application was adopted mainly at Dazhui (GV 14), Feishu (BL 13), Pishu (BL 20) and Shenshu (BL 23) in the application group. The plaster was made of Chinese herbs, including Baijiezi (semen brassicae), Xixin (asarum), Yanhusuo (corydalis tuber) and Gansui (euphorbia kansui). Buckwheat plaster without medical ingredient was used in the placebo group. The application was pasted for 2-6 h every time. On the first three days of all the three periods of dog days, treatment was used continuously. The whole period of dog days was made into one course. The changes of symptom and syndrome scores, visual analogue scale (VAS) for symptom before and after treatment and the adverse reaction with the condition disposed were observed in the two groups.

RESULTS

After treatment, the symptom and syndrome scores and VAS for symptom were improved compared with those before treatment in the two groups (all P < 0.05), and the improvements of the application group were more obvious than those of the placebo group (all P < 0.05). The short effective rate of the application group was 68.1% (113/166), which was better than 48.2% (40/83) of the placebo group (P < 0.05). The adverse reaction rates were 4.2% (7/166), 2.4% (2/83) respectively, with no statistical significance between the two groups (P > 0.05).

CONCLUSION

The dog days plaster achieves obvious effect with good safety for allergic rhinitis.

摘要

目的

评价三伏天穴位敷贴治疗变应性鼻炎的近期疗效及安全性。

方法

将249例患者随机分为敷贴组(166例)和安慰剂组(83例)。三伏天初伏第一天、中伏第一天、末伏第一天,敷贴组主要选取大椎(GV 14)、肺俞(BL 13)、脾俞(BL 20)、肾俞(BL 23)进行穴位敷贴。敷贴药物由白芥子、细辛、延胡索、甘遂等中药制成。安慰剂组采用不含药物成分的荞麦贴。每次贴敷2 - 6小时。三伏天三个阶段的前三天连续治疗,整个三伏天为1个疗程。观察两组治疗前后症状体征积分、症状视觉模拟量表(VAS)评分变化及不良反应情况。

结果

治疗后,两组症状体征积分及症状VAS评分均较治疗前改善(均P < 0.05),且敷贴组改善更明显(均P < 0.05)。敷贴组近期有效率为68.1%(113/166),优于安慰剂组的48.2%(40/83)(P < 0.05)。不良反应发生率分别为4.2%(7/166)、2.4%(2/83),两组比较差异无统计学意义(P > 0.05)。

结论

三伏贴治疗变应性鼻炎疗效显著,安全性好。

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