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[艾灸发泡结合神阙穴(CV 8)闪罐治疗阳虚型过敏性鼻炎:一项随机对照试验]

[Medicinal vesiculation combined with quick cupping at Shenque (CV 8) for allergic rhinitis with syndrome of yang deficiency: a randomized controlled trial].

作者信息

Ke Zheng-hua, Long Sheng-hua

出版信息

Zhongguo Zhen Jiu. 2014 Sep;34(9):853-6.

PMID:25509730
Abstract

OBJECTIVE

To compare the clinical efficacy differences between medicinal vesiculation combined with quick cupping at Shenque (CV 8) and regular medication for allergic rhinitis with syndrome of yang deficiency.

METHODS

Eighty-two cases were randomly divided into an observation group (42 cases) and a control group (40 cases). The observation group was treated with medicinal vesiculation combined with quick cupping at Shenque (CV 8). The medicinal vesiculation was applied at Feishu (BL 13), Gaohuang (BL 43), Fengmen (BL 12), Mingmen (GV 4) on the dog days in the summer, one treatment on the 1st dog-day, 2nd dog-day and last dog-day respectively with an interval of 10 days between two treatments. Three treatments were taken as one course, and totally one course was given. The quick cupping was applied at Shenque (CV 8), once a day, ten treatments were taken as one course, and totally three courses was given. The control group was treated with oral administration of loratadine and nasal spray of budesonide. The loratadine was given 10 mg per time, once a day for continuous 14 days; budesonide was given once a day, ten treatments were taken as one course, and totally three courses was given. The clinical efficacy in two groups after treatment was observed, and the contents of immune globulin E (IgE), interleukin-4 (IL-4), interleukin-5 (IL-5) and tumor necrosis factor-α (TNF-α) in peripheral serum were measured before and after the treatments.

RESULTS

Of all the 82 patients, 79 cases completed the treatment, and 1 patient in the observation group and 2 patients in the control group dropped out. The effective rate was 87.8% (36/41) in the observation group, which was superior to 78.9% (30/38) in the control group (P<0.05). After treatment, both groups effectively reduced the contents of IgE, IL-4, IL-5 and TNF-α, and the observation group had superior effect on reducing IgE and IL-4 to the control group (P<0.05).

CONCLUSION

The medicinal vesiculation combined with quick cupping at Shenque (CV 8) have better effect for allergic rhinitis with syndrome of yang deficiency than oral administration of loratadine and nasal spray of budesonide.

摘要

目的

比较三伏天药物发泡结合神阙穴(CV 8)闪罐与常规药物治疗阳虚型过敏性鼻炎的临床疗效差异。

方法

将82例患者随机分为观察组(42例)和对照组(40例)。观察组采用三伏天药物发泡结合神阙穴(CV 8)闪罐治疗。三伏天在肺俞穴(BL 13)、膏肓穴(BL 43)、风门穴(BL 12)、命门穴(GV 4)进行药物发泡,初伏、中伏、末伏各治疗1次,每次间隔10天,3次为1个疗程,共治疗1个疗程。神阙穴(CV 8)闪罐,每天1次,10次为1个疗程,共治疗3个疗程。对照组采用口服氯雷他定及布地奈德鼻喷雾剂治疗。氯雷他定每次10 mg,每天1次,连续服用14天;布地奈德每天1次,10次为1个疗程,共治疗3个疗程。观察两组治疗后的临床疗效,并检测治疗前后外周血清中免疫球蛋白E(IgE)、白细胞介素-4(IL-4)、白细胞介素-5(IL-5)及肿瘤坏死因子-α(TNF-α)的含量。

结果

82例患者中,79例完成治疗,观察组有1例、对照组有2例脱落。观察组有效率为87.8%(36/41),优于对照组的78.9%(30/38)(P<0.05)。治疗后,两组均有效降低了IgE、IL-4、IL-5及TNF-α的含量,且观察组在降低IgE和IL-4方面优于对照组(P<0.05)。

结论

三伏天药物发泡结合神阙穴(CV 8)闪罐治疗阳虚型过敏性鼻炎的效果优于口服氯雷他定及布地奈德鼻喷雾剂。

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