Dutschmann L, Ferreira C, De Sousa G, Miranda M I, Santos M J, Pereira M J, Lourenço M L, Soares-Costa J T, Sarmento J L
Acta Med Port. 1989 Mar-Apr;2(2):103-10.
We have studied the cardiac manifestations of connective tissue diseases. In 213 files of patients with connective tissue disease of the Department of Medicina I, Hospital Santa Maria, during 21 years. Cardiac manifestations were observed in 63 (90%) SLE. Pericarditis was the most frequent manifestation and occurred in 33 patients (43%). The cardiac manifestations were observed in 40 (41%) RA. Pericarditis appeared in 11 patients, valvulopathy in 12 patients and coronaropathy in 11 patients. In 10 of PD diagnosed patients, ECG abnormalities were the only findings. Arrhythmias, conduction disturbances, cardiac failure and coronaropathy were the cardiac manifestations of PSS in 11 patients. Polyarteritis Nodosa patients had myocardial ischemia and another had a malignant hypertension diagnosis. We found pericardial effusion in one patient and angina in another one with MCTD diagnosis. We did'nt find any cardiac manifestation in AS. Cardiac manifestations are frequent in connective tissue diseases. The ECG, ECO and pathology show abnormal findings. Although there is not clinical cardiological expression of the disease we suggest the use of ECG. ECO Holter electrocardiography and isotopic myocardial perfusion scan technics in the clinical evaluation of such patients.
我们研究了结缔组织病的心脏表现。在21年期间，对圣玛丽亚医院内科I的213例结缔组织病患者的病历进行了研究。在63例（90%）系统性红斑狼疮（SLE）患者中观察到心脏表现。心包炎是最常见的表现，33例患者（43%）出现心包炎。在40例（41%）类风湿关节炎（RA）患者中观察到心脏表现。11例患者出现心包炎，12例患者出现瓣膜病，11例患者出现冠状动脉病。在10例确诊的皮肌炎（PD）患者中，心电图异常是唯一的发现。11例系统性硬化症（PSS）患者的心脏表现为心律失常、传导障碍、心力衰竭和冠状动脉病。结节性多动脉炎患者有心肌缺血，另一例被诊断为恶性高血压。在1例混合性结缔组织病（MCTD）患者中发现心包积液，在另一例中发现心绞痛。在强直性脊柱炎（AS）患者中未发现任何心脏表现。结缔组织病中心脏表现很常见。心电图、超声心动图和病理学显示有异常发现。尽管该疾病没有临床心脏病学表现，但我们建议在对此类患者进行临床评估时使用心电图、动态心电图、超声心动图和同位素心肌灌注扫描技术。
