Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan.
Department of Therapeutic Strategy for Heart Failure, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan.
Heart Fail Rev. 2022 Jul;27(4):1001-1016. doi: 10.1007/s10741-021-10116-7. Epub 2021 May 4.
Heart failure is a major contributor to healthcare expenditures. Many clinical risk factors for the development and exacerbation of heart failure had been reported, including diabetes, renal dysfunction, and respiratory disease. In addition to these clinical parameters, the effects of social factors, such as occupation or lifestyle, and environmental factors may have a great impact on disease development and progression of heart failure. However, the current understanding of social and environmental factors as contributors to the clinical course of heart failure is insufficient. To present the knowledge of these factors to date, this comprehensive review of the literature sought to identify the major contributors to heart failure within this context. Social factors for the risk of heart failure included occupation and lifestyle, specifically in terms of the effects of specific occupations, occupational exposure to toxicities, work style, and sleep deprivation. Socioeconomic factors focused on income and education level, social status, the neighborhood environment, and marital status. Environmental factors included traffic and noise, air pollution, and other climate factors. In addition, psychological stress and behavior traits were investigated. The development of heart failure may be closely related to these factors; therefore, these data should be summarized for the context to improve their effects on patients with heart failure. The present study reviews the literature to summarize these influences.
心力衰竭是医疗支出的主要原因。许多导致心力衰竭发生和恶化的临床危险因素已被报道,包括糖尿病、肾功能障碍和呼吸系统疾病。除了这些临床参数外,社会因素(如职业或生活方式)和环境因素的影响可能对心力衰竭的发展和进展产生重大影响。然而,目前对社会和环境因素作为心力衰竭临床病程的贡献的了解还不够。为了介绍迄今为止这些因素的知识,本文献综述旨在确定这方面导致心力衰竭的主要因素。心力衰竭的社会因素包括职业和生活方式,具体涉及特定职业的影响、职业暴露于毒性物质、工作方式和睡眠剥夺、社会经济因素则集中在收入和教育水平、社会地位、邻里环境和婚姻状况。环境因素包括交通和噪音、空气污染和其他气候因素。此外,还研究了心理压力和行为特征。心力衰竭的发展可能与这些因素密切相关;因此,应汇总这些数据,以便了解其对心力衰竭患者的影响。本研究通过文献综述来总结这些影响。