Balmant Nathalie V, de Souza Reis Rejane, Pinto Oliveira Julio F, Ferman Sima, de Oliveira Santos Marceli, de Camargo Beatriz
*Multiprofissional Residency Oncology Program †Coordenação de Prevenção e Vigilância ‡Pediatric Service, Hospital do Câncer I §Pediatric Hematology and Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
J Pediatr Hematol Oncol. 2016 Apr;38(3):e88-96. doi: 10.1097/MPH.0000000000000541.
The spectrum of cancers commonly found in adolescents and young adults (AYAs) differs from those in children and adults; therefore, the childhood classification is not appropriate for this population. Here we used a newly proposed classification system to reclassify cases of AYAs from Brazilian population-based cancer registries (PBCRs) in 5 geographic regions of Brazil. We aimed to describe the cancer incidence rates within this age group according to PBCR. Using the world population, incidence rates per million were analyzed in each diagnostic subgroup according to sex and age at diagnosis (15 to 19 y, 20 to 24 y, and 25 to 29 y). The median incidence rate was 232.31 per million for females and 218.07 per million for males. Incidence increased with age, with the highest rate observed for 25- to 29-year-olds in both sexes. Carcinomas, lymphomas, and skin tumors were most frequent among AYAs. High incidence rates of cervix-uterus carcinoma were observed in most PBCRs. AYAs present epidemiological characteristics that differ from those of children, reinforcing the need for a new classification. This study describes, for the first time, the cancer incidence rate in AYAs in Brazil, and we believe that our findings represent the Brazilian profile.
青少年和青年(AYA)中常见的癌症谱与儿童和成人不同;因此,儿童癌症分类不适用于该人群。在此,我们使用一种新提出的分类系统,对来自巴西5个地理区域基于人群的癌症登记处(PBCR)的AYA病例进行重新分类。我们旨在根据PBCR描述该年龄组内的癌症发病率。以世界人口为参照,按诊断时的性别和年龄(15至19岁、20至24岁和25至29岁)分析每个诊断亚组每百万人口的发病率。女性的发病率中位数为每百万232.31例,男性为每百万218.07例。发病率随年龄增长而上升,25至29岁人群的发病率在两性中均最高。癌、淋巴瘤和皮肤肿瘤在AYA中最为常见。在大多数PBCR中观察到子宫颈癌的高发病率。AYA呈现出与儿童不同的流行病学特征,这进一步凸显了新分类的必要性。本研究首次描述了巴西AYA的癌症发病率,我们相信我们的研究结果代表了巴西的情况。