From the Department of Pathology, Taibah University, Al-Madinah Al-Munawwarah, Kingdom of Saudi Arabia.
Saudi Med J. 2021 Apr;42(4):449-453. doi: 10.15537/smj.2021.42.4.20210028.
To evaluate the incidence and pattern of cancer in adolescents and young adults (AYAs) age group in Al-Madinah Al-Munawwarah region of Saudi Arabia.
This retrospective histopathology-based study was conducted at a tertiary care center in Al-Madinah Al-Munawwarah, Saudi Arabia and comprised cases of cancers for 15 years between January 2006 and December 2020.
During the last 15-year period, 8,769 cases of cancers were diagnosed out of which 475 (5.4%) cases were registered in AYAs. Of these cases, 232 (48.8%) were males while 243 (51.2%) were females, with a male-to-female ratio of 0.9:1. The 3 most common cancer groups in the entire cohort were carcinomas (n=165; 34.7%), lymphomas (n=135; 28.4%), and leukemias (n=91; 19.2%). The most common sites in carcinomas were thyroid (n=60; 12.6%), breast (n=35; 7.4%), and gastrointestinal (n=18; 3.8%). The leading cancers in males were the lymphomas (n=74; 15.6%), leukemias (n=57; 12%), bone (n=21; 4.4%), and central nervous system (n=20; 4.2%), while in females, the most common cancers were the lymphomas (n=61; 12.8%), thyroid (n=40; 8.4%), breast (n=34; 7.2%), and leukemias (n=34; 7.2%).
Our findings are in concordance with studies in national and international literature and we believe that our study provides a baseline tool for future population-targeted studies.
评估沙特阿拉伯麦地那地区青少年和年轻成年人（AYA）癌症的发病率和模式。
这是一项在沙特麦地那的一家三级护理中心进行的基于组织病理学的回顾性研究，包括 2006 年 1 月至 2020 年 12 月期间的 15 年癌症病例。
在过去的 15 年中，诊断出 8769 例癌症，其中 475 例（5.4%）为 AYA 患者。这些病例中，男性 232 例（48.8%），女性 243 例（51.2%），男女比例为 0.9:1。整个队列中 3 个最常见的癌症组是癌（n=165；34.7%）、淋巴瘤（n=135；28.4%）和白血病（n=91；19.2%）。癌中最常见的部位是甲状腺（n=60；12.6%）、乳房（n=35；7.4%）和胃肠道（n=18；3.8%）。男性中最常见的癌症是淋巴瘤（n=74；15.6%）、白血病（n=57；12%）、骨骼（n=21；4.4%）和中枢神经系统（n=20；4.2%），而女性中最常见的癌症是淋巴瘤（n=61；12.8%）、甲状腺（n=40；8.4%）、乳房（n=34；7.2%）和白血病（n=34；7.2%）。
我们的研究结果与国内外文献中的研究一致，我们相信我们的研究为未来针对特定人群的研究提供了一个基线工具。
