Khoshchehreh Mahdi, Groves Elliott M, Tehrani David, Amin Alpesh, Patel Pranav M, Malik Shaista
Division of Cardiology, University of California, Irvine, USA; Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, USA.
Scripps Clinic, Division of Interventional Cardiology, La Jolla, CA, USA.
Int J Cardiol. 2016 May 1;210:164-72. doi: 10.1016/j.ijcard.2016.02.087. Epub 2016 Feb 17.
We assessed in-hospital mortality and utilization of invasive cardiac procedures following Acute Coronary Syndrome (ACS) admissions on the weekend versus weekdays over the past decade in the United States.
We used data from the Nationwide Inpatient Survey (2001-2011) to examine differences in all-cause in-hospital mortality between patients with a principal diagnosis of ACS admitted on a weekend versus a weekday. Adjusted and hierarchical logistic regression model analysis was then used to identify if weekend admission was associated with a decreased utilization of procedural interventions and increased subsequent complications as well.
13,988,772 ACS admissions were identified. Adjusted mortality was higher for weekend admissions for Non-ST-Elevation Acute Coronary Syndromes [OR: 1.15, 95% CI, 1.14-1.16] and only somewhat higher for ST-Elevation Myocardial Infarction [OR: 1.03; 95% CI, 1.01-1.04]. Additionally, patients were significantly less likely to receive coronary revascularization intervention/therapy on their first day of admission [OR: 0.97, 95% CI: 0.96-0.98 and OR: 0.75, 95% CI: 0.75-0.75 for STEMI and NSTE-ACS respectively]. For ACS patients admitted during the weekend who underwent procedural interventions, in-hospital mortality and complications were higher as compared to patients undergoing the same procedures on weekdays.
For ACS patients, weekend admission is associated with higher mortality and lower utilization of invasive cardiac procedures, and those who did undergo these interventions had higher rates of mortality and complications than their weekday counterparts. This data leads to the possible conclusion that access to diagnostic/interventional procedures may be contingent upon the day of admission, which may impact mortality.
我们评估了过去十年美国急性冠脉综合征(ACS)患者周末入院与工作日入院后的院内死亡率及侵入性心脏手术的使用情况。
我们使用全国住院患者调查(2001 - 2011年)的数据,研究主要诊断为ACS的患者周末入院与工作日入院的全因院内死亡率差异。然后使用调整后的分层逻辑回归模型分析来确定周末入院是否与手术干预利用率降低以及随后并发症增加有关。
共识别出13,988,772例ACS入院病例。非ST段抬高型急性冠脉综合征周末入院的调整后死亡率更高[比值比(OR):1.15,95%置信区间(CI),1.14 - 1.16],ST段抬高型心肌梗死仅略高[OR:1.03;95% CI,1.01 - 1.04]。此外,患者在入院第一天接受冠状动脉血运重建干预/治疗的可能性显著降低[STEMI和NSTE - ACS的OR分别为0.97,95% CI:0.96 - 0.98和OR:0.75,95% CI:0.75 - 0.75]。对于周末入院并接受手术干预的ACS患者,与工作日接受相同手术的患者相比,院内死亡率和并发症更高。
对于ACS患者,周末入院与更高的死亡率及侵入性心脏手术的较低利用率相关,且接受这些干预的患者比工作日入院的患者有更高的死亡率和并发症发生率。该数据可能得出结论,获得诊断/介入手术的机会可能取决于入院日期,这可能影响死亡率。