Pereira F E, Pires J G
Departamento de Patologia, Universidade Federal do Espírito Santo, Vitória, Brasil.
Braz J Med Biol Res. 1988;21(5):1019-21.
Cardiac parasympathetic denervation has been reported to occur in human and experimental T. cruzi infections. We have used acetylcholine to investigate the in vitro chronotropic sensitivity of atrial muscarinic receptors in mice chronically infected with either a reticulotropic (Y) or a myotropic (CL) strain of T. cruzi. The dose-response curves did not differ from that obtained for control mice, a result that may be due to reinnervation processes.
据报道，在人类和实验性克氏锥虫感染中会发生心脏副交感神经去神经支配。我们使用乙酰胆碱来研究慢性感染网状嗜性（Y）或肌嗜性（CL）克氏锥虫株的小鼠心房毒蕈碱受体的体外变时敏感性。剂量反应曲线与对照小鼠的曲线没有差异，这一结果可能归因于神经再支配过程。
