氮化物涂层可增强生物医学镍钛形状记忆合金的内皮化。
Nitride coating enhances endothelialization on biomedical NiTi shape memory alloy.
作者信息
Ion Raluca, Luculescu Catalin, Cimpean Anisoara, Marx Philippe, Gordin Doina-Margareta, Gloriant Thierry
机构信息
University of Bucharest, Department of Biochemistry and Molecular Biology, 91-95 Spl. Independentei, 050095 Bucharest, Romania.
National Institute for Laser, Plasma and Radiation Physics, 409 Atomistilor, P.O. Box MG-36, 077125 Magurele-Bucharest, Romania.
出版信息
Mater Sci Eng C Mater Biol Appl. 2016 May;62:686-91. doi: 10.1016/j.msec.2016.02.031. Epub 2016 Feb 10.
Surface nitriding was demonstrated to be an effective process for improving the biocompatibility of implantable devices. In this study, we investigated the benefits of nitriding the NiTi shape memory alloy for vascular stent applications. Results from cell experiments indicated that, compared to untreated NiTi, a superficial gas nitriding treatment enhanced the adhesion of human umbilical vein endothelial cells (HUVECs), cell spreading and proliferation. This investigation provides data to demonstrate the possibility of improving the rate of endothelialization on NiTi by means of nitride coating.
表面氮化被证明是一种改善可植入装置生物相容性的有效方法。在本研究中，我们研究了对用于血管支架的镍钛形状记忆合金进行氮化处理的益处。细胞实验结果表明，与未处理的镍钛合金相比，表面气体氮化处理增强了人脐静脉内皮细胞（HUVECs）的黏附、细胞铺展和增殖。本研究提供的数据证明了通过氮化物涂层提高镍钛合金内皮化速率的可能性。
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